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The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Gene Name: | pyridoxal (pyridoxine, vitamin B6) kinase |
Family/Subfamily: | Non-protein Kinase , Pyridoxine |
Synonyms: | PDXK, C21orf124, C21orf97, PNK, PRED79, Pyridoxal kinase, Pyridoxine kinase, Vitamin B6 kinase, PKH, Pyridoxamine kinase |
Target Sequences: | NM_003681 NP_003672.1 O00764 |
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