PDK3

pyruvate dehydrogenase kinase, isozyme 3

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Antibodies (52)

Proteins (9)

Type

Over-Expression Lysate (4)

Primary (52)

Recombinant (5)

Target

PDK3 (61)

Reactivity

Human (33)

Mouse (29)

Rat (8)

Bovine (6)

Chicken (3)

Chimpanzee (6)

Dog (3)

Gibbon (3)

Guinea pig (6)

Hamster (6)

Horse (3)

Monkey (6)

Pig (6)

Rabbit (3)

Xenopus (3)

Zebrafish (3)

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Application

IHC (13)

IHC-P (3)

WB (49)

Flo (1)

ELISA (24)

Host

rabbit (50)

mouse (2)

Isotype

IgG (32)

IgG2a,k (1)

IgG2b (1)

Clonality

monoclonal mc (2)

polyclonal pc (50)

Clone

2B11 (1)

Format

APC (1)

APC Conjugated (4)

Azide-free (4)

Biotin Conjugated (7)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (7)

HRP Conjugated (7)

PE Conjugated (4)

Unconjugated (21)

Epitope

aa1-30 (7)

aa387-414 (7)

C-Terminus (4)

aa74-123 (4)

aa102-351 (1)

Publications

No (60)

Yes (1)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Mouse (2)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (2)

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PDK3 Antibody (C-Terminus) LS-C111083

(4.0) Rating

(1) Publication(s)

Antibody:

PDK3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PDK3 Antibody (aa74-123) LS-C80835

Antibody:

PDK3 Rabbit anti-Human Polyclonal (aa74-123) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PDK3 Antibody LS-C163492

Antibody:

PDK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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PDK3 Antibody LS-C676239

Antibody:

PDK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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PDK3 Antibody (aa387-414) LS-C323911

Antibody:

PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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PDK3 Antibody (aa387-414, Biotin) LS-C207446

Antibody:

PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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PDK3 Antibody (aa387-414, FITC) LS-C207447

Antibody:

PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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PDK3 Antibody (aa387-414, APC) LS-C207445

Antibody:

PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

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PDK3 Antibody (aa387-414, Azide-free, HRP) LS-C207448

Antibody:

PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

PDK3 Antibody (aa387-414, PE) LS-C207449

Antibody:

PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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PDK3 Antibody LS-C409570

Antibody:

PDK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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PDK3 Antibody LS-C667567

Antibody:

PDK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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PDK3 Antibody (aa387-414) LS-C164524

Antibody:

PDK3 Rabbit anti-Mouse Polyclonal (aa387-414) Antibody

Reactivity:

Mouse

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

PDK3 Antibody (aa102-351) LS-C178567

Antibody:

PDK3 Rabbit anti-Human Polyclonal (aa102-351) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$332

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PDK3 Antibody (clone 2B11) LS-C197867

Antibody:

PDK3 Mouse anti-Human Monoclonal (2B11) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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PDK3 Antibody LS-C668212

Antibody:

PDK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

Select

PDK3 Antibody LS-C768953

Antibody:

PDK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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PDK3 Antibody LS-C671881

Antibody:

PDK3 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

PDK3 Antibody (aa1-30) LS-C323914

Antibody:

PDK3 Rabbit anti-Human Polyclonal (aa1-30) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

PDK3 Antibody (aa1-30, Biotin) LS-C207452

Antibody:

PDK3 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

PDK3 Antibody (aa1-30, APC) LS-C207451

Antibody:

PDK3 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PDK3 Antibody (aa1-30, PE) LS-C207457

Antibody:

PDK3 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

PDK3 Antibody (aa1-30, Azide-free, HRP) LS-C207454

Antibody:

PDK3 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• APC
• More...
  • PE
  • HRP, Azide-free

Select

PDK3 Antibody (Azide-free) LS-C328417

Antibody:

PDK3 Rabbit anti-Human Polyclonal (Azide-free) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated, Azide-free

Price:

200 µl/$734

Select

PDK3 Antibody LS-C780058

Antibody:

PDK3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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