PDK1

pyruvate dehydrogenase kinase, isozyme 1

Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.

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Products

ELISA Kits (5)

Type

Custom (1)

Sandwich (4)

Target

PDK1 (5)

Reactivity

Human (1)

Mouse (1)

Rat (3)

Format

96-Well Strip Plate (5)

Publications

No (5)

Sample Type

Plasma (4)

Serum (4)

Tissue Homogenates (2)

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Human PDK1 (Sandwich ELISA) ELISA Kit - LS-F12294

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat PDK1 (Sandwich ELISA) ELISA Kit - LS-F9357

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$783

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Rat PDK1 (Sandwich ELISA) ELISA Kit - LS-F12293

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat PDK1 (Sandwich ELISA) ELISA Kit - LS-F35829

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse PDK1 (Custom ELISA) ELISA Kit - LS-F15794

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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