PDK1

pyruvate dehydrogenase kinase, isozyme 1

Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress.

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Products

Antibodies (64)

Type

Primary (64)

Target

PDK1 (64)

Reactivity

Human (56)

Mouse (38)

Rat (27)

Bat (1)

Bovine (4)

Chimpanzee (3)

Dog (5)

Gibbon (3)

Guinea pig (1)

Hamster (1)

Horse (4)

Monkey (10)

Non-Human Primate (1)

Pig (3)

Rabbit (2)

Sheep (1)

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Application

IHC (22)

IHC-P (16)

WB (56)

Flo (3)

ELISA (19)

ICC (1)

IF (3)

IP (3)

Peptide-ELISA (1)

Host

rabbit (58)

mouse (5)

goat (1)

Product Group

IHCPlus (4)

Isotype

IgG (25)

IgG1 (3)

IgG2a (1)

IgG2b,k (1)

Clonality

monoclonal mc (6)

polyclonal pc (58)

Clone

3B7 (1)

4A11 (2)

Format

APC (2)

APC Conjugated (3)

Azide-free (1)

Biotin Conjugated (7)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

DY488 Conjugated (2)

DY550 Conjugated (2)

DY650 Conjugated (2)

FITC Conjugated (5)

HRP Conjugated (5)

PE Conjugated (3)

Preservative Free (2)

Unconjugated (31)

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Epitope

aa172-399 (8)

aa233-430 (8)

C-Terminus (7)

aa1-30 (7)

Internal (6)

aa287-336 (4)

80-160 aa, Internal (1)

aa123-133 (1)

aa300-400 (1)

aa350-436 (1)

aa408-421 (1)

aa421-436 (1)

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Publications

No (63)

Yes (1)

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IHC-plus™ PDK1 Antibody (aa350-436) LS-B1733

(5.0) Rating

(1) Publication(s)

Antibody:

PDK1 Rabbit anti-Human Polyclonal (aa350-436) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$460

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PDK1 Antibody (C-Terminus, Biotin) LS-C141003

Antibody:

PDK1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

0.1 ml/$416

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PDK1 Antibody (C-Terminus, DY650) LS-C141004

Antibody:

PDK1 Rabbit anti-Human Polyclonal (C-Terminus) (DY650) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

DY650 Conjugated

Price:

0.1 ml/$416

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PDK1 Antibody (C-Terminus, DY550) LS-C141007

Antibody:

PDK1 Rabbit anti-Human Polyclonal (C-Terminus) (DY550) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

DY550 Conjugated

Price:

0.1 ml/$416

Select

PDK1 Antibody (C-Terminus, DY488) LS-C141005

Antibody:

PDK1 Rabbit anti-Human Polyclonal (C-Terminus) (DY488) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

DY488 Conjugated

Price:

0.1 ml/$416

• Unconjugated
• Biotin
• DY650
• DY550
• DY488

• Unconjugated
• Biotin
• DY650
• More...
  • DY550
  • DY488

Select

PDK1 Antibody (aa421-436) LS-C26009

Antibody:

PDK1 Rabbit anti-Human Polyclonal (aa421-436) Antibody

Reactivity:

Mouse, Dog, Rat, Pig, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$529; 200 µg/$854

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IHC-plus™ PDK1 Antibody (aa300-400) LS-B689

(4.0) Rating

Antibody:

PDK1 Rabbit anti-Human Polyclonal (aa300-400) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 ml/$460

Select

PDK1 Antibody (Internal, Biotin) LS-C141008

Antibody:

PDK1 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

0.1 ml/$416

Select

PDK1 Antibody (Internal, DY650) LS-C141009

Antibody:

PDK1 Rabbit anti-Human Polyclonal (Internal) (DY650) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

DY650 Conjugated

Price:

0.1 ml/$416

Select

PDK1 Antibody (Internal, DY488) LS-C141010

Antibody:

PDK1 Rabbit anti-Human Polyclonal (Internal) (DY488) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

DY488 Conjugated

Price:

0.1 ml/$416

Select

PDK1 Antibody (Internal, DY550) LS-C141012

Antibody:

PDK1 Rabbit anti-Human Polyclonal (Internal) (DY550) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

DY550 Conjugated

Price:

0.1 ml/$416

• Unconjugated
• Biotin
• DY650
• DY488
• DY550

• Unconjugated
• Biotin
• DY650
• More...
  • DY488
  • DY550

Select

IHC-plus™ PDK1 Antibody (clone 4A11) LS-B13567

(4.0) Rating

Antibody:

PDK1 Mouse anti-Human Monoclonal (4A11) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

Select

IHC-plus™ PDK1 Antibody LS-B3690

(4.0) Rating

Antibody:

PDK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rabbit, Mouse, Dog, Rat, Pig, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

Select

PDK1 Antibody (clone 4A11) LS-C758908

Antibody:

PDK1 Mouse anti-Human Monoclonal (4A11) Antibody

Reactivity:

Mouse, Rat, Non-Human Primate, Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

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PDK1 Antibody LS-C812735

Antibody:

PDK1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Rat, Human, Monkey

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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PDK1 Antibody LS-C131340

Antibody:

PDK1 Rabbit anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

IP, WB

Format:

Unconjugated

Price:

20 µl/$453; 100 µl/$643

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PDK1 Antibody LS-C754902

Antibody:

PDK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

PDK1 Antibody LS-C754904

Antibody:

PDK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

PDK1 Antibody LS-C671875

Antibody:

PDK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

PDK1 Antibody LS-C662518

Antibody:

PDK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

PDK1 Antibody (aa408-421) LS-C313124

Antibody:

PDK1 Rabbit anti-Human Polyclonal (aa408-421) Antibody

Reactivity:

Rabbit, Guinea pig, Sheep, Bovine, Pig, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

Select

PDK1 Antibody (C-Terminus) LS-C137079

Antibody:

PDK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µl/$332

Select

PDK1 Antibody (C-Terminus) LS-C137080

Antibody:

PDK1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µl/$332

Select

PDK1 Antibody (aa1-30, Azide-free) LS-C328415

Antibody:

PDK1 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated, Azide-free

Price:

200 µl/$734

Select

PDK1 Antibody LS-C824456

Antibody:

PDK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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