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PDGF-AA

platelet-derived growth factor alpha polypeptide

Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB.

Gene Name: platelet-derived growth factor alpha polypeptide
Family/Subfamily: PDGF , not assigned-PDGF
Synonyms: PDGFA, PDGF-A, PDGF A-chain, PDGF subunit A, PDGF-1, PDGF1
Target Sequences: NM_002607 NP_002598.4 P04085

Publications (1)

1
Tourniquet use following blast-associated complex lower limb injury and traumatic amputation promotes end organ dysfunction and amplified heterotopic ossification formation. Philip J Spreadborough, Amy L Strong, John Mares, Benjamin Levi, Thomas A Davis. Journal of orthopaedic surgery and research. 2022 September;17:422. [Full Text Article] [PubMed:36123728] [PMC:PMC9484189]

☰ Filters
Products
Antibodies (66)
Primary (66)
PDGF-AA (66)
Human (50)
Mouse (18)
Rat (18)
Bovine (1)
Chimpanzee (3)
Gibbon (3)
Monkey (3)
Orangutan (3)
Pig (1)
Rabbit (1)
Rodent (1)
IHC (16)
IHC-P (5)
WB (64)
ELISA (13)
Func (1)
IP (1)
Neut (5)
Peptide-ELISA (2)
rabbit (51)
mouse (9)
goat (6)
Product Group
IHCPlus (2)
IgG (21)
IgG2b (1)
IgG2b,k (8)
monoclonal mc (9)
polyclonal pc (57)
APC (4)
APC Conjugated (6)
Azide-free (1)
Biotin Conjugated (10)
Cy3 Conjugated (4)
Cy7 Conjugated (4)
FITC Conjugated (8)
HRP Conjugated (7)
PE Conjugated (6)
Preservative Free (3)
Unconjugated (21)
aa87-211 (19)
aa90-190 (8)
aa94-194 (8)
aa60-89 (7)
C-Terminus (4)
Internal (2)
Lys154 (1)
aa105-154 (1)
No (66)
PDGF-AA Antibody - Anti-PDGFA antibody IHC of human breast, epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PDGF-AA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
PDGF-AA Antibody - Direct ELISA of PDGFA antibody This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDGF-AA Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
25 µg/$356; 50 µg/$396
PDGF-AA Antibody - Immunohistochemical analysis of PDGFA staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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PDGF-AA Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
PDGF-AA Antibody - Immunohistochemistry of paraffin-embedded Human ovarian cancer using PDGFA Polyclonal Antibody at dilution of 1:70.
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PDGF-AA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PDGF-AA Antibody - Western blot of recombinant PDGFA / PDGF-A.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDGF-AA Mouse anti-Human Monoclonal (aa87-211) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$300; 200 µl/$338; 500 µl/$466; 1 ml/$530; 2 ml/$688; 5 ml/$1,149
PDGF-AA Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PDGF-AA Mouse anti-Human Monoclonal (aa87-211) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$460
PDGF-AA Antibody - Western blot of PDGF-A antibody
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PDGF-AA Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PDGF-AA Antibody - Immunohistochemistry analysis of PDGF-A antibody in paraffin-embedded human lung carcinoma tissue.
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PDGF-AA Rabbit anti-Human Polyclonal (aa105-154) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PDGF-AA Antibody - Immunodetection Analysis: Representative blot from a previous lot. Lane 1, recombinant protein PDGFA. The membrane blot was probed with anti-PDGFA primary antibody (0.2 µg/ml). Proteins were visualized using a Donkey anti-rabbit secondary antibody conjugated to IRDye 800CW detection system. Arrows indicate recombinant protein PDGFA from E.coli cell (14kDa).
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PDGF-AA Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA, WB
Unconjugated, Preservative Free
20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452
PDGF-AA Antibody - Immunodetection Analysis: Representative blot from a previous lot. Lane 1, recombinant protein PDGFA. The membrane blot was probed with anti-PDGFA primary antibody (0.2 µg/ml). Proteins were visualized using a Donkey anti-rabbit secondary antibody conjugated to IRDye 800CW detection system. Arrows indicate recombinant protein PDGFA from E.coli cell (14kDa).
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PDGF-AA Rabbit anti-Human Polyclonal (Preservative Free) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated, Preservative Free
50 µg/$343
PDGF-AA Antibody - 1/100 staining human colon  tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary antibody.
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PDGF-AA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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PDGF-AA Rabbit anti-Human Polyclonal (aa60-89) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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PDGF-AA Rabbit anti-Human Polyclonal (aa60-89) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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PDGF-AA Rabbit anti-Human Polyclonal (aa60-89) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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PDGF-AA Rabbit anti-Human Polyclonal (aa60-89) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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PDGF-AA Rabbit anti-Human Polyclonal (aa60-89) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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PDGF-AA Rabbit anti-Human Polyclonal (aa60-89) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PDGF-AA Antibody - IHC of PDGF-A (K154) pAb in paraffin-embedded human lung carcinoma tissue.
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PDGF-AA Rabbit anti-Human Polyclonal (Lys154) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
PDGF-AA Antibody - Formalin-fixed and paraffin-embedded human brain tissue reacted with PDGFA antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PDGF-AA Rabbit anti-Human Polyclonal (aa60-89) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PDGF-AA Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using PDGFA Polyclonal Antibody at dilution of 1:40.
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PDGF-AA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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PDGF-AA Goat anti-Human Polyclonal Antibody
Bovine, Pig, Rodent, Human
Func, WB
Unconjugated
100 µg/$419; 1 mg/$913
PDGF-AA Antibody - Anti-PDGFA rabbit polyclonal antibody at 1:500 dilution. Lane A: U937 Whole Cell Lysate. Lane B: HL60 Whole Cell Lysate. Lane C: Jurkat Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG (H+L)/HRP at 1/10000 dilution. Developed using the ECL technique. Performed under reducing conditions. Predicted band size: 24 kDa. Observed band size: 24 kDa.
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PDGF-AA Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
IP, WB
Unconjugated, Preservative Free
100 µl/$412
PDGF-AA Antibody - Western blot of recombinant PDGFA / PDGF-A.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDGF-AA Rabbit anti-Mouse Polyclonal (aa94-194) Antibody
Mouse
WB
Unconjugated
100 µl/$301; 200 µl/$340; 500 µl/$470; 1 ml/$535; 2 ml/$698; 5 ml/$1,161
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PDGF-AA Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
100 µg/$842
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PDGF-AA Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
1 mg/$901
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).