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PDE7A belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE7 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Gene Name: | phosphodiesterase 7A |
Family/Subfamily: | Phosphodiesterase , PDE - cAMP-specific |
Synonyms: | PDE7A, PDE7A1, PDE7A2, Phosphodiesterase 7A, Phosphodiesterase isozyme 7, PDE7, HCP1, TM22 |
Target Sequences: | L12052 AAA35644.2 Q13946 |
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