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PDE6A / PDE6 Alpha
phosphodiesterase 6A, cGMP-specific, rod, alpha
PDE6A is the cyclic-GMP (cGMP)-specific phosphodiesterase 6A alpha subunit, expressed in cells of the retinal rod outer segment. The phosphodiesterase 6 holoenzyme is a heterotrimer composed of an alpha, beta, and two gamma subunits. cGMP is an important regulator of rod cell membrane current, and its dynamic concentration is established by phosphodiesterase 6A cGMP hydrolysis and guanylate cyclase cGMP synthesis. The protein is a subunit of a key phototransduction enzyme and participates in processes of transmission and amplification of the visual signal. Mutations in this gene have been identified as one cause of autosomal recessive retinitis pigmentosa.
| Gene Name: | phosphodiesterase 6A, cGMP-specific, rod, alpha |
| Family/Subfamily: | Phosphodiesterase , PDE - photoreceptor |
| Synonyms: | PDE6A, Alpha-PDE, CGMP phosphodiesterase alpha, CGPR-A, PDE6alpha, PDE V-B1, PDEA, Phosphodiesterase 6a, RP43, GMP-PDE alpha |
| Target Sequences: | NM_000440 NP_000431.2 P16499 |
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Products
Antibodies
(18)
Type
Primary
(18)
Target
PDE6A / PDE6 Alpha
(18)
Reactivity
Human
(18)
Mouse
(7)
Rat
(7)
Bat
(3)
Bovine
(3)
Chimpanzee
(3)
Dog
(3)
Gibbon
(3)
Guinea pig
(3)
Hamster
(4)
Horse
(3)
Monkey
(1)
Orangutan
(3)
Zebrafish
(3)
Application
IHC
(5)
IHC-P
(3)
WB
(16)
ELISA
(8)
IF
(1)
Peptide-ELISA
(1)
Host
rabbit
(18)
Product Group
IHCPlus
(1)
Isotype
IgG
(12)
Clonality
polyclonal pc
(18)
Format
APC Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(2)
FITC Conjugated
(2)
HRP Conjugated
(2)
PE Conjugated
(1)
Unconjugated
(10)
Epitope
aa308-336
(7)
aa99-148
(4)
N-Terminus
(1)
Publications
No
(18)
Fast Shipping
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Hamster, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$395
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$282; 200 µl/$350
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) Antibody
Human
WB
Unconjugated
200 µl/$734
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa308-336) Antibody
Human
WB
Unconjugated
400 µl/$393
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa99-148) Antibody
Human
WB
Unconjugated
100 µl/$424
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa99-148) (HRP) Antibody
Zebrafish, Rat, Hamster, Mouse, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa99-148) (Biotin) Antibody
Zebrafish, Rat, Hamster, Mouse, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal (aa99-148) (FITC) Antibody
Zebrafish, Rat, Hamster, Mouse, Dog, Guinea pig, Bovine, Horse, Bat, Gibbon, Orangutan, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
PDE6A / PDE6 Alpha Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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product results
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