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PDE4D

phosphodiesterase 4D, cAMP-specific

Phosphodiesterase 4D, a cAMP-specific phosphodiesterase, has been shown to affect growth and fertility, functioning of pro-inflammatory immune cells, and cholinergic stimulation of the airway and consequently the development of hyperreactive disease states such as asthma. PDE4D activity is inhibited by rolipram. At least six splice variants have been reported. Recently PDE4D has been linked to stroke, possibly through atherosclerosis, which is the primary pathological process underlying ischemic stroke (Gretarsdottir et al. 2003).

Gene Name: phosphodiesterase 4D, cAMP-specific
Family/Subfamily: Phosphodiesterase , PDE - cAMP-specific
Synonyms: PDE4D, ACRDYS2, DPDE3, HSPDE4D, PDE43, Pde-ivd, PDE4DN2, Phosphodiesterase 4d, STRK1
Target Sequences: NM_006203 NP_006194.2 Q08499

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Products
Proteins (10)
Over-Expression Lysate (6)
Recombinant (4)
PDE4D (10)
No (10)
GST (1)
GST, N-terminus (1)
His-GST (1)
Myc-DDK (Flag) (7)
Human (7)
293T Cells (3)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
PDE4D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
76.3 kDa
20 µg/$215
PDE4D Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PDE4D Protein - Purified recombinant protein PDE4D was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
76.3 kDa
20 µg/$1,107
PDE4D Protein - Recombinant Phosphodiesterase 4D, cAMP Specific By SDS-PAGE
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E. coli
His-GST
56.1 kDa
10 µg/$279; 50 µg/$430; 100 µg/$687; 200 µg/$857; 1 mg/$1,956; 500 µg/$1,499; 5 mg/$2,997; 2 mg/$2,142
PDE4D Protein - 12.5% SDS-PAGE of human PDE4D stained with Coomassie Blue
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Wheat Germ Extract
GST
82.72 kDa
2 µg/$439
PDE4D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
77.3 kDa
20 µg/$215
PDE4D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
66.9 kDa
20 µg/$150
PDE4D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
76.3 kDa
100 µg/$710
PDE4D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
77.3 kDa
100 µg/$710
PDE4D Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
66.9 kDa
100 µg/$494
Viewing 1-10 of 10 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).