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PDE3B

phosphodiesterase 3B, cGMP-inhibited

Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.

Gene Name: phosphodiesterase 3B, cGMP-inhibited
Family/Subfamily: Phosphodiesterase , PDE - cAMP/cGMP dual-specific, cGMP-inhibited
Synonyms: PDE3B, CGIPDE1, CGI-PDE B, CGIP1, HcGIP1, Phosphodiesterase 3b, Phosphodiesterase type 3B, RPDE-3B, RcGIP1
Target Sequences: NM_000922 NP_000913.2 Q13370

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
PDE3B (4)
No (4)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
PDE3B Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PDE3B Protein - Purified recombinant protein PDE3B was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
124.2 kDa
20 µg/$1,107
PDE3B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
124.2 kDa
20 µg/$215
PDE3B Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
124.2 kDa
100 µg/$710
Viewing 1-4 of 4 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).