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PDE1A

phosphodiesterase 1A, calmodulin-dependent

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).

Gene Name: phosphodiesterase 1A, calmodulin-dependent
Family/Subfamily: Phosphodiesterase , PDE - cAMP/cGMP dual-specific, Ca/Calmodulin-dependent
Synonyms: PDE1A, 61 kDa Cam-PDE, 59 kDa CaM-PDE, Cam-PDE 1A, HCAM-1, HCAM1, HSPDE1A, Phosphodiesterase 1a, CAM-PDE-1A
Target Sequences: NM_005019 NP_005010.2 P54750

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Products
Proteins (6)
Over-Expression Lysate (2)
Recombinant (4)
PDE1A (6)
No (6)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
PDE1A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
100 µg/$494
PDE1A Protein - 12.5% SDS-PAGE of human PDE1A stained with Coomassie Blue
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Wheat Germ Extract
GST
88.7 kDa
10 µg/$479; 25 µg/$670
PDE1A Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PDE1A Protein - Recombinant  Phosphodiesterase 1A, Calmodulin Dependent By SDS-PAGE
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E. coli
His-T7
40.4 kDa
10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113
PDE1A Protein - Purified recombinant protein PDE1A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$1,107
PDE1A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
62.1 kDa
20 µg/$150
Viewing 1-6 of 6 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).