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PDE1A

phosphodiesterase 1A, calmodulin-dependent

Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]).

Gene Name:	phosphodiesterase 1A, calmodulin-dependent
Family/Subfamily:	Phosphodiesterase , PDE - cAMP/cGMP dual-specific, Ca/Calmodulin-dependent
Synonyms:	PDE1A, 61 kDa Cam-PDE, 59 kDa CaM-PDE, Cam-PDE 1A, HCAM-1, HCAM1, HSPDE1A, Phosphodiesterase 1a, CAM-PDE-1A
Target Sequences:	NM_005019 NP_005010.2 P54750

Human PDE1A (Sandwich ELISA) ELISA Kit - LS-F9599

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$730

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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