PDE12

phosphodiesterase 12

Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. This enzyme degraded triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the The 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme induces reduction of viral replication in Hela cells, thus counteracting the antiviral pathway probably by inhibiting the 2-5A system.

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Products

Antibodies (25)

Proteins (4)

ELISA Kits (1)

Type

Over-Expression Lysate (2)

Primary (25)

Recombinant (2)

Sandwich (1)

Target

PDE12 (30)

Reactivity

Human (17)

Mouse (15)

Rat (6)

Bat (3)

Bovine (6)

Chicken (3)

Chimpanzee (3)

Dog (3)

Gibbon (3)

Guinea pig (6)

Hamster (3)

Horse (6)

Monkey (3)

Pig (6)

Rabbit (3)

Zebrafish (3)

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Application

WB (25)

Flo (7)

ELISA (7)

IF (1)

Host

rabbit (25)

Isotype

IgG (8)

Clonality

polyclonal pc (25)

Format

96-Well Strip Plate (1)

APC (1)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (7)

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Epitope

aa290-602 (8)

aa362-390 (7)

C-Terminus (4)

aa368-417 (4)

aa559-609 (1)

Publications

No (30)

Sample Type

Plasma (1)

Serum (1)

Tissue Homogenates (1)

Tag

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (2)

Mouse (1)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Select

PDE12 Antibody (aa362-390) LS-C163466

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa362-390) Antibody

Reactivity:

Human

Applications:

Flo, WB

Format:

Unconjugated

Price:

400 µl/$393

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PDE12 Antibody (aa368-417) LS-C186696

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa368-417) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PDE12 Antibody (aa368-417, HRP) LS-C457433

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa368-417) (HRP) Antibody

Reactivity:

Zebrafish, Pig, Horse, Mouse, Guinea pig, Bovine, Rat, Human, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PDE12 Antibody (aa368-417, Biotin) LS-C457431

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa368-417) (Biotin) Antibody

Reactivity:

Zebrafish, Pig, Horse, Mouse, Guinea pig, Bovine, Rat, Human, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PDE12 Antibody (aa368-417, FITC) LS-C457432

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa368-417) (FITC) Antibody

Reactivity:

Zebrafish, Pig, Horse, Mouse, Guinea pig, Bovine, Rat, Human, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PDE12 Antibody LS-C667544

Antibody:

PDE12 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

PDE12 Antibody (aa362-390) LS-C323884

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa362-390) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

PDE12 Antibody (aa362-390, Biotin) LS-C207421

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa362-390) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

PDE12 Antibody (aa362-390, FITC) LS-C207422

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa362-390) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PDE12 Antibody (aa362-390, APC) LS-C207419

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa362-390) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PDE12 Antibody (aa362-390, Azide-free, HRP) LS-C207424

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa362-390) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

PDE12 Antibody (aa362-390, PE) LS-C207425

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa362-390) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

PDE12 Antibody (aa290-602) LS-C373386

Antibody:

PDE12 Rabbit anti-Mouse Polyclonal (aa290-602) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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PDE12 Antibody (aa290-602, HRP) LS-C713441

Antibody:

PDE12 Rabbit anti-Mouse Polyclonal (aa290-602) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

Select

PDE12 Antibody (aa290-602, Biotin) LS-C688596

Antibody:

PDE12 Rabbit anti-Mouse Polyclonal (aa290-602) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

Select

PDE12 Antibody (aa290-602, FITC) LS-C695595

Antibody:

PDE12 Rabbit anti-Mouse Polyclonal (aa290-602) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

Select

PDE12 Antibody (aa290-602, PE) LS-C727509

Antibody:

PDE12 Rabbit anti-Mouse Polyclonal (aa290-602) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

PDE12 Antibody (aa290-602, Cy3) LS-C704424

Antibody:

PDE12 Rabbit anti-Mouse Polyclonal (aa290-602) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

PDE12 Antibody (aa290-602, APC) LS-C741534

Antibody:

PDE12 Rabbit anti-Mouse Polyclonal (aa290-602) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

Select

PDE12 Antibody (aa290-602, APC, Cy7) LS-C736423

Antibody:

PDE12 Rabbit anti-Mouse Polyclonal (aa290-602) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• Cy3
• APC
• More...
  • APC, Cy7

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • Cy3
  • APC
  • APC, Cy7

Select

PDE12 Antibody (C-Terminus) LS-C111507

Antibody:

PDE12 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PDE12 Antibody (C-Terminus, HRP) LS-C457437

Antibody:

PDE12 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

PDE12 Antibody (C-Terminus, Biotin) LS-C457434

Antibody:

PDE12 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PDE12 Antibody (C-Terminus, FITC) LS-C457435

Antibody:

PDE12 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Rat, Hamster, Pig, Horse, Bat, Gibbon, Human, Monkey

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PDE12 Antibody (aa559-609) LS-C763148

Antibody:

PDE12 Rabbit anti-Human Polyclonal (aa559-609) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295

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