PC / Pyruvate Carboxylase

pyruvate carboxylase

PC / Pyruvate Carboxylase is pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.

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Products

Proteins (8)

Type

Over-Expression Lysate (4)

Recombinant (4)

Target

PC / Pyruvate Carboxylase (8)

Publications

No (8)

Tag

GST, N-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (6)

Species

Human (6)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (4)

Wheat Germ Extract (1)

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Human PC / Pyruvate Carboxylase Protein (Recombinant His-T7) (aa36-486) - LS-G25887

Source:

E. coli

Tag:

His-T7

Molecular Weight:

53.6 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Human PC / Pyruvate Carboxylase Protein (Recombinant GST, N-terminus) (aa1-104) - LS-G59516

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

2 µg/$439

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Human PC / Pyruvate Carboxylase Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66784

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

127.4 kDa

Price:

20 µg/$1,107

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Human PC / Pyruvate Carboxylase Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66785

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

127.3 kDa

Price:

20 µg/$1,107

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Human PC / Pyruvate Carboxylase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78492

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.63 kDa

Price:

20 µg/$150

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Human PC / Pyruvate Carboxylase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78494

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.63 kDa

Price:

20 µg/$215

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PC / Pyruvate Carboxylase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119446

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.63 kDa

Price:

100 µg/$710

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PC / Pyruvate Carboxylase Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99224

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

129.63 kDa

Price:

100 µg/$494

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