PBX1

pre-B-cell leukemia homeobox 1

Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression.

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Products

Antibodies (30)

Proteins (5)

Type

Over-Expression Lysate (2)

Primary (30)

Recombinant (3)

Target

PBX1 (35)

Reactivity

Human (30)

Mouse (8)

Rat (7)

Bat (1)

Bovine (4)

Chicken (1)

Chimpanzee (3)

Dog (1)

Gibbon (3)

Hamster (1)

Horse (1)

Monkey (4)

Pig (4)

Rabbit (1)

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Application

IHC (9)

IHC-P (3)

WB (22)

Flo (6)

ELISA (3)

ICC (1)

IF (15)

IP (2)

Peptide-ELISA (2)

PMA (4)

Host

rabbit (15)

mouse (14)

goat (1)

Isotype

IgG (14)

IgG1 (13)

IgG2a,k (1)

Clonality

monoclonal mc (14)

polyclonal pc (16)

Clone

4A2 (1)

OTI1C11 (2)

OTI1D9 (2)

OTI1H5 (2)

OTI4D1 (2)

UMAB110 (2)

UMAB111 (2)

Format

Biotin Conjugated (2)

Carrier-free (6)

FITC Conjugated (2)

HRP Conjugated (2)

Preservative Free (1)

Unconjugated (24)

Epitope

N-Terminus (5)

aa313-327 (1)

Publications

No (34)

Yes (1)

Tag

GST, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (4)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (2)

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PBX1 Antibody (clone 4A2) LS-C133363

(4.1) Rating

(2) Publication(s)

Antibody:

PBX1 Mouse anti-Human Monoclonal (4A2) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$423

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PBX1 Antibody (clone OTI1C11) LS-C173044

Antibody:

PBX1 Mouse anti-Human Monoclonal (OTI1C11) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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PBX1 Antibody (clone OTI1C11, Carrier-free) LS-C786134

Antibody:

PBX1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1C11) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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PBX1 Antibody (clone UMAB110) LS-C796759

Antibody:

PBX1 Mouse anti-Human Monoclonal (UMAB110) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA

Format:

Unconjugated

Price:

100 µl/$493

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PBX1 Antibody (clone UMAB110, Carrier-free) LS-C796761

Antibody:

PBX1 Mouse anti-Human Monoclonal (Carrier-free) (UMAB110) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA

Format:

Unconjugated, Carrier-free

Price:

100 µg/$539

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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PBX1 Antibody LS-C670953

Antibody:

PBX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PBX1 Antibody (FITC) LS-C670952

Antibody:

PBX1 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• FITC

• Unconjugated
• FITC

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PBX1 Antibody (clone UMAB111) LS-C796760

Antibody:

PBX1 Mouse anti-Human Monoclonal (UMAB111) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA

Format:

Unconjugated

Price:

100 µl/$493

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PBX1 Antibody (clone UMAB111, Carrier-free) LS-C796763

Antibody:

PBX1 Mouse anti-Human Monoclonal (Carrier-free) (UMAB111) Antibody

Reactivity:

Human

Applications:

IF, IHC, PMA

Format:

Unconjugated, Carrier-free

Price:

100 µg/$539

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

PBX1 Antibody (clone OTI1D9) LS-C172991

Antibody:

PBX1 Mouse anti-Human Monoclonal (OTI1D9) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

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PBX1 Antibody (clone OTI1D9, Carrier-free) LS-C786065

Antibody:

PBX1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1D9) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

PBX1 Antibody (clone OTI4D1) LS-C173146

Antibody:

PBX1 Mouse anti-Human Monoclonal (OTI4D1) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

PBX1 Antibody (clone OTI4D1, Carrier-free) LS-C797436

Antibody:

PBX1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4D1) Antibody

Reactivity:

Human

Applications:

Flo, IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

PBX1 Antibody LS-C667493

Antibody:

PBX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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Human PBX1 Protein (Recombinant GST, N-terminus) (aa213-321) - LS-G59515

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Molecular Weight:

37.7 kDa

Price:

10 µg/$479; 25 µg/$670

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PBX1 Antibody LS-C488653

Antibody:

PBX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

Select

PBX1 Antibody (clone OTI1H5) LS-C337367

Antibody:

PBX1 Mouse anti-Human Monoclonal (OTI1H5) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

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PBX1 Antibody (clone OTI1H5, Carrier-free) LS-C786038

Antibody:

PBX1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1H5) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

PBX1 Antibody LS-C349244

Antibody:

PBX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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PBX1 Antibody (N-Terminus) LS-C74189

Antibody:

PBX1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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PBX1 Antibody LS-C803659

Antibody:

PBX1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PBX1 Antibody LS-C74190

Antibody:

PBX1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

Select

PBX1 Antibody (aa313-327) LS-C113024

Antibody:

PBX1 Goat anti-Human Polyclonal (aa313-327) Antibody

Reactivity:

Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

Select

PBX1 Antibody (N-Terminus) LS-C40287

Antibody:

PBX1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PBX1 Antibody (Preservative Free) LS-C815685

Antibody:

PBX1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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