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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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PBK / TOPK

PDZ binding kinase

TOPK is a TOPK protein kinase which may be associated with cell signaling in lymphokine-activated killer T (T-LAK) cells and spermatogenesis. Studies suggest that mitotic phosphorylation is required for its catalytic activity. Similar to MEK3/MAP2K3 and MKK6/MAP2K6, activated TOPK phosphorylates the MAP kinase p38. At least two mRNA variants have been identified - a major full-length form and a minor spliced form at the 5'-site, both encoding the same protein. TOPK has been shown to be upregulated in Burkitt's lymphoma and other highly proliferative malignant cells.

Gene Name: PDZ binding kinase
Family/Subfamily: Protein Kinase , TOPK
Synonyms: PBK, CT84, MAPKK-like protein kinase, PDZ binding kinase, PDZ-binding kinase, Cancer/testis antigen 84, Nori-3, SPK, TOPK
Target Sequences: NM_018492 NP_060962.2 Q96KB5

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Products
Antibodies (49)
Primary (49)
PBK / TOPK (49)
Human (49)
Mouse (16)
Rat (7)
Bat (3)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (4)
Pig (3)
Rabbit (3)
Xenopus (3)
IHC (26)
IHC-P (14)
WB (43)
Flo (4)
ELISA (31)
ICC (3)
IF (8)
IP (1)
Peptide-ELISA (2)
rabbit (39)
mouse (10)
Product Group
IHCPlus (3)
Ig (1)
IgG (34)
IgG1 (1)
IgG2a,k (3)
IgG2b (2)
IgG2b,k (3)
monoclonal mc (10)
polyclonal pc (39)
10 (1)
1E11 (1)
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aa286-317 (7)
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aa1-322 (1)
aa200-250 (1)
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aa79-322 (1)
p9 (1)
No (49)
PBK / TOPK Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
PBK / TOPK Mouse anti-Human Monoclonal (2C8) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$485
PBK / TOPK Antibody - Immunoperoxidase of monoclonal antibody to PBK on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
Select
PBK / TOPK Mouse anti-Human Monoclonal (3A7) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
PBK / TOPK Antibody - PBK Antibody in Immunohistochemistry (IHC)
Select
PBK / TOPK Mouse anti-Human Monoclonal (2C8) Antibody
Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µl/$503
PBK / TOPK Antibody - Immunoperoxidase of monoclonal antibody to PBK on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
Select
PBK / TOPK Mouse anti-Human Monoclonal (3A11) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
PBK / TOPK Antibody - Immunoperoxidase of monoclonal antibody to PBK on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
Select
PBK / TOPK Mouse anti-Human Monoclonal (4A10) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
PBK / TOPK Antibody - Immunoperoxidase of monoclonal antibody to PBK on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
Select
PBK / TOPK Mouse anti-Human Monoclonal (1E11) Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
100 µg/$423
PBK / TOPK Antibody - Anti-PBK / TOPK antibody IHC of human thymus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Select
PBK / TOPK Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo, IF, IHC, WB
Unconjugated
100 µg/$331
Select
PBK / TOPK Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$688
PBK / TOPK Antibody - Immunohistochemistry of paraffin-embedded human tonsil using antibody at 1:100 dilution.
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa1-322) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
Select
PBK / TOPK Rabbit anti-Human Polyclonal (pThr9) Antibody
Human
ELISA, Flo, ICC, WB
Unconjugated
100 µl/$689
PBK / TOPK Antibody - Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa286-317) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$460
PBK / TOPK Antibody - PBK antibody IHC-paraffin: Mouse Testis Tissue.
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa71-322) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa286-317) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa286-317) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa286-317) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa286-317) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa286-317) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
Select
PBK / TOPK Rabbit anti-Human Polyclonal (aa286-317) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PBK / TOPK Antibody - Immunoperoxidase of monoclonal antibody to PBK on formalin-fixed paraffin-embedded human cholangiocarcinoma. [antibody concentration 3 ug/ml]
Select
PBK / TOPK Mouse anti-Human Monoclonal (5E1) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
100 µg/$423
PBK / TOPK Antibody - Immunoperoxidase of monoclonal antibody to PBK on formalin-fixed paraffin-embedded human cholangiocarcinoma. [antibody concentration 3 ug/ml]
Select
PBK / TOPK Mouse anti-Human Monoclonal (6E3) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
100 µg/$423
PBK / TOPK Antibody - Western blot of Phospho-PBK (T9) antibody
Select
PBK / TOPK Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PBK / TOPK Antibody - Western blot of PBK antibody
Select
PBK / TOPK Rabbit anti-Human Polyclonal (1-80 aa) Antibody
Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PBK / TOPK Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using PBK/TOPK (Ab-9) antibody.
Select
PBK / TOPK Rabbit anti-Human Polyclonal (p9) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PBK / TOPK Antibody - IHC of PBK/TOPK (I4) pAb in paraffin-embedded human breast tissue.
Select
PBK / TOPK Rabbit anti-Human Polyclonal (Ile4) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Viewing 1-25 of 49 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).