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This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box gene 4 is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
Gene Name: | paired box 4 |
Synonyms: | PAX4, KPD, Paired box protein Pax-4, Paired domain gene 4, Paired box 4, Paired box gene 4, MODY9 |
Target Sequences: | NM_006193 NP_006184.2 O43316 |
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