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Poly [ADP-ribose] polymerase using NAD+ as a substrate to transfer ADP-ribose onto glutamic acid residues of a protein acceptor; repeated rounds of ADP-ribosylation leads to the formation of poly(ADPribose) chains on the protein, thereby altering the function of the target protein. May play a role in the adaptive response to chemical exposure (TCDD) and thereby mediates certain effects of the chemicals.
Gene Name: | TCDD-inducible poly(ADP-ribose) polymerase |
Synonyms: | TIPARP, ARTD14, DDF1, PART14, PARP7, Poly [ADP-ribose] polymerase 7, PARP-7, DKFZP434J214, PARP-1, RM1 |
Target Sequences: | NP_849223.2 |
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