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Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Gene Name: | par-6 family cell polarity regulator beta |
Synonyms: | PARD6B, PAR6B, PAR-6 beta, PAR-6B |
Target Sequences: | Q9BYG5 Q9BYG5 |
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