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Catalytic subunit of a TRAMP-like complex which has a poly(A) RNA polymerase activity and is involved in a post-transcriptional quality control mechanism. Polyadenylation with short oligo(A) tails is required for the degradative activity of the exosome on several of its nuclear RNA substrates. Has no terminal uridylyltransferase activity, and does not play a role in replication-dependent histone mRNA degradation via uridylation.
Gene Name: | PAP associated domain containing 7 |
Synonyms: | PAPD7, DNA polymerase kappa, DNA polymerase sigma, LAK1, POLS, LAK-1, Terminal uridylyltransferase 5, TRF4, TUTase 5, TRF4-1, TRF41, TUTASE5 |
Target Sequences: | NM_006999 NP_008930.1 Q5XG87 |
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