Pan Cytokeratin

Keratin / Cytokeratin

Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. The term "cytokeratin" began to be used in the late 1970s (for example, see "Intermediate-sized filaments of human endothelial cells" by Franke, Schmid, Osborn and Weber) when the protein subunits of keratin intermediate filaments inside cells were first being identified and characterized. In 2006 a new systematic nomenclature for keratins was created and now the proteins previously called "cytokeratins" are simply called keratins. Micrograph showing low molecular weight cytokeratin (LMWCK) staining of intermediate trophoblast (placental tissue) and endometrial glands. There are two types of cytokeratins: the basic type I cytokeratins and the acidic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Basic or neutral cytokeratins include CK1, CK2, CK3, CK4, CK5, CK6, CK7, and CK8. Acidic cytokeratins are CK9, CK10, CK12, CK13, CK14, CK16, CK17, CK18, CK19 and CK20. The cytokeratins can be divided into low versus high molecular weight solely based on their molecular weight. Expression of these cytokeratins is frequently organ or tissue specific. As an example, CK7 is typically expressed in the ductal epithelium of the genitourinary (GU) tract and CK20 most commonly in the gastrointestinal (GI) tract. Anatomic pathologists employ such distinctions to detect the cell of origin of various tumors.

Pan Cytokeratin Target Details

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Products

ELISA Kits (8)

Type

Competitive EIA (2)

Sandwich (6)

Target

Pan Cytokeratin (8)

Reactivity

Human (2)

Mouse (1)

Chicken (1)

Guinea pig (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Format

96-Well Strip Plate (8)

Publications

No (8)

Sample Type

Plasma (3)

Serum (3)

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Human Pan Cytokeratin (Sandwich ELISA) ELISA Kit - LS-F49196

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human Pan Cytokeratin (Competitive EIA) ELISA Kit - LS-F28828

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Chicken Pan Cytokeratin (Sandwich ELISA) ELISA Kit - LS-F46478

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Guinea pig Pan Cytokeratin (Sandwich ELISA) ELISA Kit - LS-F46479

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine Pan Cytokeratin (Sandwich ELISA) ELISA Kit - LS-F46480

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit Pan Cytokeratin (Sandwich ELISA) ELISA Kit - LS-F46482

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Sheep Pan Cytokeratin (Sandwich ELISA) ELISA Kit - LS-F46483

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

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Mouse Pan Cytokeratin (Competitive EIA) ELISA Kit - LS-F28566

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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