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PAIP1

poly(A) binding protein interacting protein 1

Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain.

Gene Name: poly(A) binding protein interacting protein 1
Synonyms: PAIP1, PABC1-interacting protein 1, PABP-interacting protein 1, PAIP-1
Target Sequences: NM_006451 NP_006442.2 Q9H074

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Products
Proteins (7)
Over-Expression Lysate (4)
Recombinant (3)
PAIP1 (7)
No (7)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (5)
Human (5)
293T Cells (2)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
PAIP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
41.8 kDa
100 µg/$494
PAIP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
45.5 kDa
100 µg/$494
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293T Cells
Myc-DDK (Flag)
45.5 kDa
20 µg/$150
PAIP1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
41.8 kDa
20 µg/$150
PAIP1 Protein - 12.5% SDS-PAGE of human PAIP1 stained with Coomassie Blue
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Wheat Germ Extract
GST
72 kDa
10 µg/$479; 25 µg/$670
PAIP1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PAIP1 Protein - Purified recombinant protein PAIP1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
45.5 kDa
20 µg/$1,107
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).