Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
P4HA1 is a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene Name: | prolyl 4-hydroxylase, alpha polypeptide I |
Synonyms: | P4HA1, 4-PH alpha-1, C-P4Halpha(I), p4HA, p4HA1 |
Target Sequences: | NM_000917 NP_000908.2 P13674 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.