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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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P2RX6 / P2X6
purinergic receptor P2X, ligand-gated ion channel, 6
P2RX6 / P2X6 belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.
| Gene Name: | purinergic receptor P2X, ligand-gated ion channel, 6 |
| Family/Subfamily: | Ion Channel , P2X receptor |
| Synonyms: | P2RX6, ATP receptor, p2RXL1, p2X purinoceptor 6, p2RX6, p2X6, p2X6 purinoceptor, p2XM, Purinergic receptor, Purinoreceptor P2X6, Skeletal muscle-expressed P2X, p2X receptor 6, p2X-like 1, Purinergic receptor P2X-like 1, Purinoceptor P2X6 |
| Target Sequences: | NM_005446 NP_005437.2 O15547 |
Publications (2)
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