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P2RX6 / P2X6

purinergic receptor P2X, ligand-gated ion channel, 6

P2RX6 / P2X6 belongs to the family of P2X receptors, which are ATP-gated ion channels and mediate rapid and selective permeability to cations. This gene is predominantly expressed in skeletal muscle, and regulated by p53. The encoded protein is associated with VE-cadherin at the adherens junctions of human umbilical vein endothelial cells. Alternative splicing results in multiple transcript variants. A related pseudogene, which is also located on chromosome 22, has been identified.

Gene Name: purinergic receptor P2X, ligand-gated ion channel, 6
Family/Subfamily: Ion Channel , P2X receptor
Synonyms: P2RX6, ATP receptor, p2RXL1, p2X purinoceptor 6, p2RX6, p2X6, p2X6 purinoceptor, p2XM, Purinergic receptor, Purinoreceptor P2X6, Skeletal muscle-expressed P2X, p2X receptor 6, p2X-like 1, Purinergic receptor P2X-like 1, Purinoceptor P2X6
Target Sequences: NM_005446 NP_005437.2 O15547

Publications (2)

1
Time-of-day-dependent expression of purinergic receptors in mouse suprachiasmatic nucleus. Lommen J, Stahr A, Ingenwerth M, Ali AAH, von Gall C. Cell and tissue research. 2017 (IHC, WB; Mouse, Human) [Full Text Article] [PubMed:28547658] [PMC:PMC5579179] Related Antibodies: LS-C94426.
2
Spatiotemporal and anatomical analyses of P2X receptor-mediated neuronal and glial processing of sensory signals in the rat dorsal horn. Aoyama R, Okada Y, Yokota S, Yasui Y, Fukuda K, Shinozaki Y, Yoshida H, Nakamura M, Chiba K, Yasui Y, Kato F, Toyama Y. Pain. 2011 Sep;152:2085-97. [Full Text Article] [PubMed:21669492] Related Antibodies: LS-B154.

☰ Filters
Antibodies (19)
Proteins (4)
Over-Expression Lysate (4)
Primary (19)
P2RX6 / P2X6 (23)
Human (17)
Mouse (2)
Rat (4)
Bovine (3)
Chimpanzee (6)
Gibbon (3)
Guinea pig (3)
Horse (3)
Monkey (3)
Pig (3)
Rabbit (3)
IHC (6)
IHC-P (4)
WB (19)
ELISA (6)
rabbit (19)
Product Group
IHCPlus (1)
IgG (9)
polyclonal pc (19)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (8)
aa198-226 (7)
aa35-84 (4)
aa66-115 (4)
Cytoplasmic Domain (1)
Extracellular Domain (1)
aa387-406 (1)
No (21)
Yes (2)
Myc-DDK (Flag) (4)
Human (2)
293T Cells (2)
HEK 293 Cells (2)
P2RX6 / P2X6 Antibody - Anti-P2RX6 / P2X6 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1.25 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa66-115) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
P2RX6 / P2X6 Antibody - Anti-P2RX6 / P2X6 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1.25 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa66-115) (HRP) Antibody
Rabbit, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
P2RX6 / P2X6 Antibody - Anti-P2RX6 / P2X6 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1.25 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa66-115) (Biotin) Antibody
Rabbit, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
P2RX6 / P2X6 Antibody - Anti-P2RX6 / P2X6 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 1.25 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa66-115) (FITC) Antibody
Rabbit, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
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P2RX6 / P2X6 Rabbit anti-Mouse Polyclonal (Cytoplasmic Domain) Antibody
Mouse, Rat
IHC, WB
Unconjugated
500 µg/$393
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, WB
Unconjugated
500 µg/$393
P2RX6 / P2X6 Antibody - P2RX6 Antibody western blot of 293 cell line lysates (35 ug/lane). The P2RX6 antibody detected the P2RX6 protein (arrow).
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) Antibody
Human
WB
Unconjugated
400 µl/$393
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa198-226) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
P2RX6 / P2X6 Antibody - P2RX6 / P2X6 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
P2RX6 / P2X6 Antibody - P2RX6 / P2X6 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Human, Chimpanzee
WB
HRP Conjugated
100 µl/$469
P2RX6 / P2X6 Antibody - P2RX6 / P2X6 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Human, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
P2RX6 / P2X6 Antibody - P2RX6 / P2X6 antibody Western blot of ACHN lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
P2RX6 / P2X6 Antibody - Western blot analysis of extracts of mouse pancreas, using P2RX6 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal Antibody
Mouse
WB
Unconjugated
20 µl/$275; 100 µl/$389
P2RX6 / P2X6 Antibody - WB of P2RX6 / P2X6 antibody. Lane 1: U87 Cell Lysate. Lane 2: 22RV1 Cell Lysate. Lane 3: JURKAT Cell Lysate. Lane 4: HT1080 Cell Lysate.
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P2RX6 / P2X6 Rabbit anti-Human Polyclonal (aa387-406) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
P2RX6 / P2X6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
45.6 kDa
100 µg/$494
P2RX6 / P2X6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
48.6 kDa
100 µg/$710
P2RX6 / P2X6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
45.6 kDa
20 µg/$150
P2RX6 / P2X6 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
48.6 kDa
20 µg/$215
Viewing 1-23 of 23 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).