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P2RX4 / P2X4
purinergic receptor P2X, ligand-gated ion channel, 4
P2RX4 / P2X4 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants, some protein-coding and some not protein-coding, have been found for this gene.
| Gene Name: | purinergic receptor P2X, ligand-gated ion channel, 4 |
| Family/Subfamily: | Ion Channel , P2X receptor |
| Synonyms: | P2RX4, ATP receptor, p2X purinoceptor 4, p2X4R, p2RX4, p2X receptor 4, p2X4, p2X4 purinoceptor, Purinergic receptor P2X4, Purinoceptor P2X4, Purinergic receptor, p2X receptor, subunit 4 |
| Target Sequences: | NM_002560 NP_002551.2 Q99571 |
Publications (3)
1
Role of mast cell activation in inducing microglial cells to release neurotrophin. Yuan H, Zhu X, Zhou S, Chen Q, Zhu X, Ma X, He X, Tian M, Shi X. Journal of neuroscience research. 2010 88:1348-54.
[PubMed:20025063]
Related Antibodies: LS-C112758.
2
Regenerative protein thymosin beta-4 is a novel regulator of purinergic signaling. Freeman KW, Bowman BR, Zetter BR. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2011 25:907-15.
[PubMed:21106936]
Related Antibodies: LS-C112758.
3
Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells. Cody L Dunton, J Todd Purves, Francis M Hughes Jr, Huixia Jin, Jiro Nagatomi. International urology and nephrology. 2018 September;50:1607-1617. [Full Text Article]
[PubMed:30099658]
[PMC:PMC6129973]
Related Antibodies: LS-C501672.
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P2RX4 / P2X4
(21)
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(15)
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(13)
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(14)
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(16)
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(2)
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(2)
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(10)
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(4)
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(1)
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(1)
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(1)
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(1)
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(19)
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(3)
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(1)
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(2)
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Purified
(2)
P2RX4 / P2X4 Goat anti-Mouse Polyclonal (aa56-69) Antibody
Mouse, Dog, Rat, Hamster, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
P2RX4 / P2X4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
P2RX4 / P2X4 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
P2RX4 / P2X4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
P2RX4 / P2X4 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
P2RX4 / P2X4 Goat anti-Human Polyclonal (aa367-380) Antibody
Bovine, Pig, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
P2RX4 / P2X4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
P2RX4 / P2X4 Rabbit anti-Human Polyclonal (aa35-84) Antibody
Human
WB
Unconjugated
100 µl/$424
P2RX4 / P2X4 Rabbit anti-Human Polyclonal (aa35-84) (HRP) Antibody
Chicken, Zebrafish, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Gibbon
WB
HRP Conjugated
100 µl/$469
P2RX4 / P2X4 Rabbit anti-Human Polyclonal (aa35-84) (Biotin) Antibody
Chicken, Zebrafish, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Gibbon
WB
Biotin Conjugated
100 µl/$469
P2RX4 / P2X4 Rabbit anti-Human Polyclonal (aa35-84) (FITC) Antibody
Chicken, Zebrafish, Guinea pig, Bovine, Human, Monkey, Chimpanzee, Gibbon
WB
FITC Conjugated
100 µl/$469
293T Cells
Myc-DDK (Flag)
43.2 kDa
20 µg/$150
P2RX4 / P2X4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
P2RX4 / P2X4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
P2RX4 / P2X4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
P2RX4 / P2X4 Rabbit anti-Rat Polyclonal (aa370-388) Antibody
Rat
ELISA, WB
Unconjugated
50 µl/$738
P2RX4 / P2X4 Rabbit anti-Human Polyclonal (aa262-388) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
HEK 293 Cells
Myc-DDK (Flag)
43.2 kDa
20 µg/$1,107
Wheat Germ Extract
GST
68.42 kDa
2 µg/$439
HEK 293 Cells
Myc-DDK (Flag)
43.2 kDa
100 µg/$494
E. coli
6His-SUMO, N-terminus
100 µg/$1,128; 20 µg/$721
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