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OXTR / Oxytocin Receptor

oxytocin receptor

The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.

Gene Name: oxytocin receptor
Family/Subfamily: GPCR , Vasopressin/oxytocin
Synonyms: OXTR, Oxytocin receptor, Oxt-r, OT-R
Target Sequences: NM_000916 NP_000907.2 P30559

Publications (2)

1
The distribution of oxytocin and the oxytocin receptor in rat brain: relation to regions active in migraine. Karin Warfvinge, Diana Krause, Lars Edvinsson. The journal of headache and pain. 2020 Feb;21:10. [Full Text Article] [PubMed:32028899] [PMC:PMC7006173] Related Antibodies: LS-C373020.
2
Evidence that oxytocin exerts anxiolytic effects via oxytocin receptor expressed in serotonergic neurons in mice. Yoshida M, Takayanagi Y, Inoue K, Kimura T, Young LJ, Onaka T, Nishimori K. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2009 Feb;29:2259-71. [Full Text Article] [PubMed:19228979] Related Antibodies: LS-A246.

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Products
Antibodies (47)
Primary (47)
OXTR / Oxytocin Receptor (47)
Human (30)
Mouse (20)
Rat (14)
IHC (6)
IHC-P (4)
WB (37)
Flo (2)
ELISA (17)
IF (1)
Peptide-ELISA (1)
rabbit (46)
goat (1)
Product Group
GPCR Database Antibodies (4)
IHCPlus (2)
PathPlus Neuro (2)
IgG (16)
polyclonal pc (47)
APC (3)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (5)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (18)
aa272-377 (8)
aa43-129 (8)
aa6-75 (8)
aa8-36 (7)
C-Terminus (2)
N-Terminus (2)
Cytoplasmic Domain (1)
aa320-389 (1)
aa64-74 (1)
No (45)
Yes (2)
OXTR / Oxytocin Receptor Antibody - Anti-Oxytocin Receptor antibody IHC of human uterus, term. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
OXTR / Oxytocin Receptor Antibody - Anti-Oxytocin Receptor antibody IHC of human uterus, term. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
OXTR / Oxytocin Receptor Antibody - Human Ganglion: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Fast Shipping
OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
OXTR / Oxytocin Receptor Antibody - Anti-Oxytocin Receptor antibody IHC of human uterus, pregnant. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Fast Shipping
OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
OXTR / Oxytocin Receptor Antibody - Western blot of OXTR / Oxytocin Receptor antibody.
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OXTR / Oxytocin Receptor Rabbit anti-Rat Polyclonal (aa43-129) Antibody
Rat
WB
Unconjugated
100 µl/$317; 200 µl/$363; 500 µl/$515; 1 ml/$591; 2 ml/$816; 5 ml/$1,331
OXTR / Oxytocin Receptor Antibody - OXTR Antibody western blot of mouse heart tissue lysates (35 ug/lane). The OXTR antibody detected the OXTR protein (arrow).
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (aa8-36) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
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OXTR / Oxytocin Receptor Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat
ELISA, WB
Unconjugated
100 µg/$832
OXTR / Oxytocin Receptor Antibody - Immunofluorescent analysis of HepG2 cells using OXTR Antibody at a dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF
Unconjugated
50 µg/$294; 100 µg/$360
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (aa320-389) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
100 µg/$351
OXTR / Oxytocin Receptor Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using OXTR Polyclonal Antibody at dilution of 1:40.
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (aa8-36) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (aa8-36) (Biotin) Antibody
Mouse, Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (aa8-36) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (aa8-36) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (aa8-36) (PE) Antibody
Mouse, Human
ELISA, WB
PE Conjugated
200 µl/$952
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal (aa8-36) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
OXTR / Oxytocin Receptor Antibody - Western blot analysis of Mouse heart tissue, using OXTR Polyclonal Antibody at dilution of 1:866.
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OXTR / Oxytocin Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
OXTR / Oxytocin Receptor Antibody - OXTR / Oxytocin Receptor antibody flow cytometric analysis of paraformaldehyde fixed Jurkat cells (blue line), permeabilized with 0.5% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (1ug/ml). IgG control: Unimmunized goat IgG (black line) followed by Alexa Fluor 488 secondary antibody.
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OXTR / Oxytocin Receptor Goat anti-Human Polyclonal (aa64-74) Antibody
Human
Flo, Peptide-ELISA
Unconjugated
100 µg/$503
OXTR / Oxytocin Receptor Antibody - Western blot of recombinant OXTR / Oxytocin Receptor.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OXTR / Oxytocin Receptor Rabbit anti-Mouse Polyclonal (aa6-75) Antibody
Mouse
WB
Unconjugated
100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261
OXTR / Oxytocin Receptor Antibody - Western blot of recombinant OXTR / Oxytocin Receptor.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OXTR / Oxytocin Receptor Rabbit anti-Mouse Polyclonal (aa6-75) (HRP) Antibody
Mouse
WB
HRP Conjugated
100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639
OXTR / Oxytocin Receptor Antibody - Western blot of recombinant OXTR / Oxytocin Receptor.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OXTR / Oxytocin Receptor Rabbit anti-Mouse Polyclonal (aa6-75) (Biotin) Antibody
Mouse
WB
Biotin Conjugated
100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387
OXTR / Oxytocin Receptor Antibody - Western blot of recombinant OXTR / Oxytocin Receptor.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OXTR / Oxytocin Receptor Rabbit anti-Mouse Polyclonal (aa6-75) (FITC) Antibody
Mouse
WB
FITC Conjugated
100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765
OXTR / Oxytocin Receptor Antibody - Western blot of recombinant OXTR / Oxytocin Receptor.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OXTR / Oxytocin Receptor Rabbit anti-Mouse Polyclonal (aa6-75) (Cy3) Antibody
Mouse
WB
Cy3 Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
OXTR / Oxytocin Receptor Antibody - Western blot of recombinant OXTR / Oxytocin Receptor.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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OXTR / Oxytocin Receptor Rabbit anti-Mouse Polyclonal (aa6-75) (PE) Antibody
Mouse
WB
PE Conjugated
100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).