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OX1R / Orexin Receptor 1
hypocretin (orexin) receptor 1
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.
| Gene Name: | hypocretin (orexin) receptor 1 |
| Family/Subfamily: | GPCR , Orexin |
| Synonyms: | HCRTR1, Hcrt receptor 1, Hypocretin receptor 1, Hypocretin type 1 receptor, Hypocretin receptor-1, Orexin receptor type 1, Orexin type 1 receptor, Orexin-1 receptor, OX1 receptor, Orexin a receptor, Orexin receptor-1, OX-R1, Orexin receptor 1, Ox1-R, OX1R, Hypocretin (orexin) receptor 1, Hypocretin receptor type 1, Ox-1-R |
| Target Sequences: | NM_001525 NP_001516.2 O43613 |
Publications (2)
1
Yokukansan (Kampo medicinal formula) prevents the development of morphine tolerance by inhibiting the secretion of orexin A. Ayami Katayama, Yasuaki Kanada, Mana Tsukada, Yuko Akanuma, Haruka Takemura, Takahiro Ono, Hiroki Suga, Hitoshi Mera, Tadashi Hisamitsu, Masataka Sunagawa. Integrative medicine research. 2018 Jun;;7:141-148. [Full Text Article]
[PubMed:29989049]
[PMC:PMC6035380]
Related Antibodies: LS-C385249.
2
Human adipose tissue is a putative direct target of daytime orexin with favorable metabolic effects: A cross-sectional study. Nir Goldstein, Hiroshi Tsuneki, Nikhil Bhandarkar, Eleonora Aimaretti, Yulia Haim, Kanta Kon, Kiyofumi Sato, Tsutomu Wada, Idit F Liberty, Boris Kirshtein, Oleg Dukhno, Nitzan Maixner, Yftach Gepner, Toshiyasu Sasaoka, Assaf Rudich. Obesity (Silver Spring, Md.). 2021 November;29:1857-1867. [Full Text Article]
[PubMed:34472713]
Related Antibodies: LS-C292046.
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OX1R / Orexin Receptor 1
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Fast Shipping
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Dog, Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Rabbit, Bovine, Rat, Pig, Human
IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Rat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa221-270) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (270-350 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa256-291) Antibody
Human
Peptide-ELISA, WB
Unconjugated
400 µl/$393
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa1-80) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$380
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF
Unconjugated
100 µg/$357
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa298-347) Antibody
Mouse, Rat, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa270-298) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa270-298) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa270-298) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa270-298) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa270-298) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa270-298) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (200-280 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal (aa231-280) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
OX1R / Orexin Receptor 1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
OX1R / Orexin Receptor 1 Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat, Human
ELISA, WB
Unconjugated
50 µg/$907
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