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OTUD7B / Cezanne
OTU domain containing 7B
Negative regulator of the non-canonical NF-kappa-B pathway that acts by mediating deubiquitination of TRAF3, an inhibitor of the NF-kappa-B pathway, thereby acting as a negative regulator of B-cell responses. In response to non-canonical NF-kappa-B stimuli, deubiquitinates 'Lys-48'-linked polyubiquitin chains of TRAF3, preventing TRAF3 proteolysis and over-activation of non-canonical NF-kappa-B. Negatively regulates mucosal immunity against infections. Mediates deubiquitination of EGFR. Has deubiquitinating activity toward 'Lys-11', 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. In vitro, has preference for 'Lys-11'-linked polyubiquitin chains; however such data are unsure in vivo. Hydrolyzes both linear and branched forms of polyubiquitin.
| Gene Name: | OTU domain containing 7B |
| Synonyms: | OTUD7B, CEZANNE, OTU domain containing 7B, ZA20D1, Zinc finger protein Cezanne |
| Target Sequences: | NM_020205 NP_064590.2 Q6GQQ9 |
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Antibodies
(30)
Proteins
(4)
Type
Over-Expression Lysate
(2)
Primary
(30)
Recombinant
(2)
Target
OTUD7B / Cezanne
(34)
Reactivity
Human
(30)
Mouse
(7)
Rat
(7)
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(6)
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(6)
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(3)
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(6)
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(6)
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(3)
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(3)
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(11)
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(3)
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(25)
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(9)
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(23)
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(18)
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(6)
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(1)
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monoclonal mc
(7)
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(23)
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(1)
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(2)
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(2)
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(2)
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(1)
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(1)
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(4)
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(4)
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(4)
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(1)
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(16)
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aa757-784
(7)
aa449-729
(6)
aa559-608
(4)
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(4)
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(34)
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(1)
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(3)
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(3)
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293T Cells
(1)
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(2)
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(1)
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Purified
(1)
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa559-608) Antibody
Human
WB
Unconjugated
100 µl/$397
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa559-608) (HRP) Antibody
Mouse, Dog, Bovine, Rat, Pig, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$442
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa559-608) (Biotin) Antibody
Mouse, Dog, Bovine, Rat, Pig, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$442
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa559-608) (FITC) Antibody
Mouse, Dog, Bovine, Rat, Pig, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$442
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa757-784) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
OTUD7B / Cezanne Mouse anti-Human Monoclonal (2B4) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
OTUD7B / Cezanne Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
OTUD7B / Cezanne Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
OTUD7B / Cezanne Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa757-784) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa757-784) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa757-784) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa757-784) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa757-784) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa757-784) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
OTUD7B / Cezanne Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF
Unconjugated
100 µl/$412
OTUD7B / Cezanne Mouse anti-Human Monoclonal (aa449-729) (OTI2E2) Antibody
Human
WB
Unconjugated
100 µl/$434
OTUD7B / Cezanne Mouse anti-Human Monoclonal (aa449-729) (Carrier-free) (OTI2E2) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
OTUD7B / Cezanne Mouse anti-Human Monoclonal (aa449-729) (OTI3D10) Antibody
Human
WB
Unconjugated
100 µl/$434
OTUD7B / Cezanne Mouse anti-Human Monoclonal (aa449-729) (Carrier-free) (OTI3D10) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
OTUD7B / Cezanne Mouse anti-Human Monoclonal (aa449-729) (OTI3B5) Antibody
Human
WB
Unconjugated
100 µl/$434
OTUD7B / Cezanne Mouse anti-Human Monoclonal (aa449-729) (Carrier-free) (OTI3B5) Antibody
Human
WB
Unconjugated, Carrier-free
100 µg/$511
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa612-661) Antibody
Human
WB
Unconjugated
100 µl/$424
OTUD7B / Cezanne Rabbit anti-Human Polyclonal (aa612-661) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
OTUD7B / Cezanne Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
120 µl/$403; 200 µl/$529
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of 34
product results
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