Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
OTUD5 is a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.
Gene Name: | OTU domain containing 5 |
Synonyms: | OTUD5, Deubiquitinating enzyme A, Deubiquinating enzyme A, DUBA, OTU domain containing 5 |
Target Sequences: | Q96G74 Q96G74 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.