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Osteocalcin
bone gamma-carboxyglutamate (gla) protein
Osteocalcin (BGLAP) is secreted by osteoblasts and plays a role in metabolic regulation. It is pro-osteoblastic (bone-building). It is also implicated in bone mineralization and calcium ion homeostasis. Osteocalcin acts as a hormone in the body, causing beta cells in the pancreas to release more insulin, and at the same time directing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. It may play a role in male fertility, enhancing the synthesis of testosterone.
| Gene Name: | bone gamma-carboxyglutamate (gla) protein |
| Synonyms: | BGLAP, Bone Gla protein, BGP, OC, Osteocalcin |
| Target Sequences: | BG752923 NP_954642.1 P02818 |
Publications (11)
1
Collagen-Hydroxyapatite Scaffolds Induce Human Adipose Derived Stem Cells Osteogenic Differentiation In Vitro. Calabrese G, Giuffrida R, Fabbi C, Figallo E, Lo Furno D, Gulino R, Colarossi C, Fullone F, Giuffrida R, Parenti R, Memeo L, Forte S. PloS one. 2016 11:e0151181. (WB, ELISA, IHC-Fr; Bovine, Human)
[Full Text Article]
[PubMed:26982592]
[PMC:PMC4794180]
2
Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Langen UH, Pitulescu ME, Kim JM, Enriquez-Gasca R, Sivaraj KK, Kusumbe AP, Singh A, Di Russo J, Bixel MG, Zhou B, Sorokin L, Vaquerizas JM, Adams RH. Nature cell biology. 2017 March;19:189-201. (Mouse)
[Full Text Article]
[PubMed:28218908]
[PMC:PMC5580829]
3
R-spondin-2 is a Wnt agonist that regulates osteoblast activity and bone mass. Knight MN, Karuppaiah K, Lowe M, Mohanty S, Zondervan RL, Bell S, Ahn J, Hankenson KD. Bone research. 2018 August;6:24. [Full Text Article]
[PubMed:30131881]
[PMC:PMC6089978]
☰ Filters
Products
Proteins
(13)
Type
Over-Expression Lysate
(2)
Recombinant
(11)
Target
Osteocalcin
(13)
Publications
No
(13)
Tag
6His-SUMO, N-terminus
(1)
GST
(2)
GST, N-terminus
(1)
His
(1)
His-GST
(3)
His-GST-S
(1)
His-T7
(1)
Myc-DDK (Flag)
(3)
Species
Chicken
(1)
Human
(5)
Mouse
(2)
Rabbit
(1)
Rat
(3)
Source
293T Cells
(1)
E. coli
(8)
HEK 293 Cells
(2)
Wheat Germ Extract
(2)
Purification
Purified
(2)
Low Endotoxin Level
Low endotoxin level
(1)
E. coli
His-GST
41.0 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
E. coli
His-GST
40.8 kDa
10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
E. coli
GST
33 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
293T Cells
Myc-DDK (Flag)
8.7 kDa
20 µg/$150
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
8.7 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
8.7 kDa
100 µg/$494
E. coli
75 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
8.36 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
E. coli
His-T7
12.4 kDa
10 µg/$289; 50 µg/$490; 100 µg/$782; 200 µg/$977; 1 mg/$2,114; 500 µg/$1,640; 5 mg/$3,417; 2 mg/$2,304
E. coli
His-GST-S
38.4 kDa
10 µg/$289; 50 µg/$492; 100 µg/$785; 200 µg/$982; 1 mg/$2,119; 500 µg/$1,646; 5 mg/$3,431; 2 mg/$2,309
Wheat Germ Extract
GST
37.4 kDa
10 µg/$479; 25 µg/$670
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
E. coli
His-GST
41.7 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
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