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Infectious Disease
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OSMR / IL-31R-Beta
oncostatin M receptor
OSMR / IL-31R-Beta is a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | oncostatin M receptor |
| Synonyms: | OSMR, IL-31R-beta, IL-31R subunit beta, PLCA1, Oncostatin M receptor, OSMRB, IL-31 receptor subunit beta, IL-31RB |
| Target Sequences: | NM_003999 NP_003990.1 Q99650 |
Publications (4)
1
Dermal Periostin: A New Player in Itch of Prurigo Nodularis. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, Paolo Romanelli, Gil Yosipovitch. Acta dermato-venereologica. 2020 November; [Full Text Article]
[PubMed:33236123]
Related Antibodies: LS-B11477.
2
Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages. Takashi Hashimoto, Christina Dorothy Kursewicz, Rachel Alison Fayne, Sonali Nanda, Serena Maya Shah, Leigh Nattkemper, Hiroo Yokozeki, Gil Yosipovitch. The Journal of investigative dermatology. 2020 Apr;;140:850-859.e3. [Full Text Article]
[PubMed:31626785]
Related Antibodies: LS-B11477.
3
Itch intensity in prurigo nodularis is closely related to dermal interleukin-31, oncostatin M, IL-31 receptor alpha and oncostatin M receptor beta. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, John F Paolini, Paolo Romanelli, Gil Yosipovitch. Experimental dermatology. 2021 June;30:804-810. [Full Text Article]
[PubMed:33428793]
Related Antibodies: LS-B11477.
☰ Filters
Products
Proteins
(12)
Type
Over-Expression Cell Culture Supernatant
(1)
Recombinant
(11)
Target
OSMR / IL-31R-Beta
(12)
Publications
No
(12)
Tag
6His, C-terminus
(2)
6His, N-terminus
(1)
GST
(1)
GST, N-terminus
(1)
His
(1)
His, N-Terminal
(1)
His,C-terminus
(1)
His-GST-S
(1)
His-T7
(2)
Myc-DDK (Flag)
(1)
Species
Human
(9)
Mouse
(2)
Rat
(1)
Source
E. coli
(3)
HEK 293 Cells
(4)
Human Cells
(2)
Mammalian Cells
(1)
Wheat Germ Extract
(2)
Purification
Purified
(4)
Low Endotoxin Level
Low endotoxin level
(4)
E. coli
His-T7
31.5 kDa
10 µg/$274; 50 µg/$397; 100 µg/$635; 200 µg/$792; 1 mg/$1,864; 500 µg/$1,419; 5 mg/$2,826; 2 mg/$2,047
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
40 kDa
20 µg/$1,107
E. coli
His-GST-S
57.9 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
HEK 293 Cells
6His, N-terminus
81 kDa
200 µl/$283
Wheat Germ Extract
GST
65.9 kDa
10 µg/$479; 25 µg/$670
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
82.6 kDa
100 µg/$721
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
83.7 kDa
200 µg/$926; 1 mg/$2,785
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
82.0 kDa
10 µg/$269; 50 µg/$367
HEK 293 Cells
His, N-Terminal
~120 kDa
10 µg/$289; 50 µg/$360; 200 µg/$646
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
82.03kD
10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157
E. coli
His-T7
31.6 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
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