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OSMR / IL-31R-Beta

oncostatin M receptor

OSMR / IL-31R-Beta is a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: oncostatin M receptor
Synonyms: OSMR, IL-31R-beta, IL-31R subunit beta, PLCA1, Oncostatin M receptor, OSMRB, IL-31 receptor subunit beta, IL-31RB
Target Sequences: NM_003999 NP_003990.1 Q99650

Publications (4)

1
Dermal Periostin: A New Player in Itch of Prurigo Nodularis. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, Paolo Romanelli, Gil Yosipovitch. Acta dermato-venereologica. 2020 November; [Full Text Article] [PubMed:33236123] Related Antibodies: LS-B11477.
2
Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages. Takashi Hashimoto, Christina Dorothy Kursewicz, Rachel Alison Fayne, Sonali Nanda, Serena Maya Shah, Leigh Nattkemper, Hiroo Yokozeki, Gil Yosipovitch. The Journal of investigative dermatology. 2020 Apr;;140:850-859.e3. [Full Text Article] [PubMed:31626785] Related Antibodies: LS-B11477.
3
Itch intensity in prurigo nodularis is closely related to dermal interleukin-31, oncostatin M, IL-31 receptor alpha and oncostatin M receptor beta. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, John F Paolini, Paolo Romanelli, Gil Yosipovitch. Experimental dermatology. 2021 June;30:804-810. [Full Text Article] [PubMed:33428793] Related Antibodies: LS-B11477.
4
SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation. Robson MJ, Turner RC, Naser ZJ, McCurdy CR, O'Callaghan JP, Huber JD, Matsumoto RR. Experimental neurology. 2014 254:180-9. (WB; Human) [Full Text Article] [PubMed:24508558] [PMC:PMC4241368] Related Antibodies: LS-C73895.
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Products
ELISA Kits (18)
Competitive EIA (1)
Custom (4)
Sandwich (12)
Sandwich CLIA (1)
OSMR / IL-31R-Beta (18)
Human (8)
Mouse (2)
Rat (2)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
Sheep (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (2)
96-Well Strip Plate (15)
No (18)
Cell Culture Supernatants (1)
Cell Lysates (1)
Plasma (7)
Serum (7)
Tissue Homogenates (2)
Urine (1)
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates, Urine
1 Plate/$798
OSMR / IL-31R-Beta ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$669
OSMR / IL-31R-Beta ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
OSMR / IL-31R-Beta ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
OSMR / IL-31R-Beta ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
312.5 - 20000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$582
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Guinea pig
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
OSMR / IL-31R-Beta ELISA Kit
Select
Sandwich
96-Well Strip Plate
Sheep
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
OSMR / IL-31R-Beta ELISA Kit
Select
Custom
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
1 Plate/$823
Viewing 1-18 of 18 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).