Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Quick Order
OSMR / IL-31R-Beta
oncostatin M receptor
OSMR / IL-31R-Beta is a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Dermal Periostin: A New Player in Itch of Prurigo Nodularis. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, Paolo Romanelli, Gil Yosipovitch. Acta dermato-venereologica. 2020 November; [Full Text Article]
[PubMed:33236123]
Related Antibodies: LS-B11477.
2
Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages. Takashi Hashimoto, Christina Dorothy Kursewicz, Rachel Alison Fayne, Sonali Nanda, Serena Maya Shah, Leigh Nattkemper, Hiroo Yokozeki, Gil Yosipovitch. The Journal of investigative dermatology. 2020 Apr;;140:850-859.e3. [Full Text Article]
[PubMed:31626785]
Related Antibodies: LS-B11477.
3
Itch intensity in prurigo nodularis is closely related to dermal interleukin-31, oncostatin M, IL-31 receptor alpha and oncostatin M receptor beta. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, John F Paolini, Paolo Romanelli, Gil Yosipovitch. Experimental dermatology. 2021 June;30:804-810. [Full Text Article]
[PubMed:33428793]
Related Antibodies: LS-B11477.
4
SN79, a sigma receptor antagonist, attenuates methamphetamine-induced astrogliosis through a blockade of OSMR/gp130 signaling and STAT3 phosphorylation. Robson MJ, Turner RC, Naser ZJ, McCurdy CR, O'Callaghan JP, Huber JD, Matsumoto RR. Experimental neurology. 2014 254:180-9. (WB; Human)[Full Text Article]
[PubMed:24508558]
[PMC:PMC4241368]
Related Antibodies: LS-C73895.
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.
PLEASE NOTE
For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.
The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).