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OSMR / IL-31R-Beta
oncostatin M receptor
OSMR / IL-31R-Beta is a member of the type I cytokine receptor family. The encoded protein heterodimerizes with interleukin 6 signal transducer to form the type II oncostatin M receptor and with interleukin 31 receptor A to form the interleukin 31 receptor, and thus transduces oncostatin M and interleukin 31 induced signaling events. Mutations in this gene have been associated with familial primary localized cutaneous amyloidosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Gene Name: | oncostatin M receptor |
| Synonyms: | OSMR, IL-31R-beta, IL-31R subunit beta, PLCA1, Oncostatin M receptor, OSMRB, IL-31 receptor subunit beta, IL-31RB |
| Target Sequences: | NM_003999 NP_003990.1 Q99650 |
Publications (4)
1
Dermal Periostin: A New Player in Itch of Prurigo Nodularis. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, Paolo Romanelli, Gil Yosipovitch. Acta dermato-venereologica. 2020 November; [Full Text Article]
[PubMed:33236123]
Related Antibodies: LS-B11477.
2
Mechanisms of Itch in Stasis Dermatitis: Significant Role of IL-31 from Macrophages. Takashi Hashimoto, Christina Dorothy Kursewicz, Rachel Alison Fayne, Sonali Nanda, Serena Maya Shah, Leigh Nattkemper, Hiroo Yokozeki, Gil Yosipovitch. The Journal of investigative dermatology. 2020 Apr;;140:850-859.e3. [Full Text Article]
[PubMed:31626785]
Related Antibodies: LS-B11477.
3
Itch intensity in prurigo nodularis is closely related to dermal interleukin-31, oncostatin M, IL-31 receptor alpha and oncostatin M receptor beta. Takashi Hashimoto, Leigh A Nattkemper, Hei Sung Kim, Christina D Kursewicz, Emilie Fowler, Serena M Shah, Sonali Nanda, Rachel A Fayne, John F Paolini, Paolo Romanelli, Gil Yosipovitch. Experimental dermatology. 2021 June;30:804-810. [Full Text Article]
[PubMed:33428793]
Related Antibodies: LS-B11477.
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OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa612-661) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa612-661) (HRP) Antibody
Dog, Guinea pig, Horse, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa612-661) (Biotin) Antibody
Dog, Guinea pig, Horse, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa612-661) (FITC) Antibody
Dog, Guinea pig, Horse, Gibbon, Human, Monkey, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
OSMR / IL-31R-Beta Rat anti-Mouse Monoclonal (aa24-738) (PE) (12K147) Antibody
Mouse
Flo
PE Conjugated
100 Tests/$836
OSMR / IL-31R-Beta Mouse anti-Human Monoclonal (PE) (AN-V2) Antibody
Human
Flo
PE Conjugated
100 Tests/$453
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
OSMR / IL-31R-Beta Rabbit anti-Mouse Polyclonal (aa410-652) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
OSMR / IL-31R-Beta Goat anti-Human Polyclonal Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µg/$962
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa513-760) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
OSMR / IL-31R-Beta Mouse anti-Human Monoclonal (8F3H8B2) Antibody
Human
ELISA, IHC-P, IP
Unconjugated
50 µl/$460
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, Flo
Unconjugated
20 µl/$271; 100 µl/$412
OSMR / IL-31R-Beta Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
OSMR / IL-31R-Beta Mouse anti-Human Monoclonal (aa28-739) (APC) (10K58 ) Antibody
Human
Flo
APC Conjugated
100 Tests/$890
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa21-70) Antibody
Human
WB
Unconjugated
100 µl/$424
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal (aa21-70) (FITC) Antibody
Dog, Human, Chimpanzee
WB
FITC Conjugated
100 µl/$469
E. coli
His-T7
31.5 kDa
10 µg/$274; 50 µg/$397; 100 µg/$635; 200 µg/$792; 1 mg/$1,864; 500 µg/$1,419; 5 mg/$2,826; 2 mg/$2,047
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
OSMR / IL-31R-Beta Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA
Unconjugated
100 µl/$412
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Mouse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
OSMR / IL-31R-Beta Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
100 µg/$351
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product results
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