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OSBPL5 is a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified.
Gene Name: | oxysterol binding protein-like 5 |
Synonyms: | OSBPL5, OBPH1, ORP-5, ORP5, OSBP-related protein 5, KIAA1534 |
Target Sequences: | NM_020896 NP_065947.1 Q9H0X9 |
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