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OSBP2 contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene Name: | oxysterol binding protein 2 |
Synonyms: | OSBP2, KIAA1664, ORP4, OSBP-related protein 4, ORP-4, Oxysterol binding protein 2, OSBPL4, OSBPL1, Oxysterol-binding protein 2 |
Target Sequences: | NM_030758 NP_110385.1 Q969R2 |
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