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Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4.
Gene Name: | osteosarcoma amplified 9, endoplasmic reticulum lectin |
Synonyms: | OS9, Amplified in osteosarcoma 9, Endoplasmic reticulum lectin 2, ERLEC2, Erlectin 2, OS-9, Protein OS-9 |
Target Sequences: | NM_006812 NP_006803.1 Q13438 |
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