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ORC5

origin recognition complex, subunit 5

The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene Name:	origin recognition complex, subunit 5
Synonyms:	ORC5, ORC5L, ORC5P, ORC5T
Target Sequences:	NM_002553 NP_002544.1 O43913

Publications (1)

Human NOC3 is essential for DNA replication licensing in human cells. Man-Hei Cheung, Aftab Amin, Rentian Wu, Yan Qin, Lan Zou, Zhiling Yu, Chun Liang. Cell cycle (Georgetown, Tex.). 2019 Mar;18:605-620. [Full Text Article] [PubMed:30741601] [PMC:PMC6464578] Related Antibodies: LS-C178970.

Human ORC5 Protein (Recombinant GST) - LS-G132114

Tag:

GST

Molecular Weight:

36.74kDa

Price:

2 µg/$439

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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