OPRK1 / Kappa Opioid Receptor

opioid receptor, kappa 1

G-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.

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Products

Antibodies (37)

Proteins (3)

ELISA Kits (2)

Type

Over-Expression Lysate (2)

Primary (37)

Recombinant (1)

Sandwich (2)

Target

OPRK1 / Kappa Opioid Receptor (42)

Reactivity

Human (30)

Mouse (21)

Rat (24)

Dog (1)

Horse (1)

Monkey (2)

Pig (3)

Rabbit (1)

Application

IHC (8)

IHC-P (5)

WB (32)

ELISA (14)

ICC (2)

IF (1)

Peptide-ELISA (6)

Host

rabbit (35)

mouse (1)

goat (1)

Product Group

GPCR Database Antibodies (2)

IHCPlus (3)

Isotype

IgG (28)

IgG1 (1)

Clonality

monoclonal mc (1)

polyclonal pc (36)

Format

96-Well Microplate (1)

96-Well Strip Plate (1)

APC Conjugated (1)

Azide-free (2)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (29)

Epitope

aa181-209 (7)

C-Terminus (6)

N-Terminus (4)

Internal (2)

pSer369 (2)

290-370 aa, C-terminal (1)

310-390 aa (1)

Ab-369 (1)

Extracellular Domain (1)

aa312-361 (1)

aa321-370 (1)

aa331-380 (1)

aa366-380 (1)

aa367-379 (1)

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Publications

No (40)

Yes (2)

Sample Type

Cell Lysates (1)

Tissue Homogenates (2)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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IHC-plus™ OPRK1 / Kappa Opioid Receptor Antibody (C-Terminus) LS-A230

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(5.0) Rating

(1) Publication(s)

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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IHC-plus™ OPRK1 / Kappa Opioid Receptor Antibody (Extracellular Domain) LS-A228

Fast Shipping

(4.0) Rating

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody

Reactivity:

Rabbit, Dog, Rat, Horse, Human, Monkey

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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OPRK1 / Kappa Opioid Receptor Antibody (310-390 aa) LS-C380901

(4.0) Rating

(1) Publication(s)

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Mouse Polyclonal (310-390 aa) Antibody

Reactivity:

Mouse, Rat

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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IHC-plus™ OPRK1 / Kappa Opioid Receptor Antibody (aa366-380) LS-B6883

(4.0) Rating

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (aa366-380) Antibody

Reactivity:

Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$460

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OPRK1 / Kappa Opioid Receptor Antibody LS-C37887

Antibody:

OPRK1 / Kappa Opioid Receptor Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

100 µg/$884

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OPRK1 / Kappa Opioid Receptor Antibody (phospho-Ser369) LS-C199175

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Mouse Polyclonal (pSer369) Antibody

Reactivity:

Mouse, Rat

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Rat OPRK1 / Kappa Opioid Receptor (Sandwich ELISA) ELISA Kit - LS-F32210

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$579

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OPRK1 / Kappa Opioid Receptor Antibody (aa331-380) LS-C199174

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Mouse Polyclonal (aa331-380) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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OPRK1 / Kappa Opioid Receptor Antibody LS-C805790

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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OPRK1 / Kappa Opioid Receptor Antibody (C-Terminus) LS-C37882

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Rat Polyclonal (C-Terminus) Antibody

Reactivity:

Rat

Applications:

ELISA, ICC, WB

Format:

Unconjugated

Price:

100 µl/$587

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OPRK1 / Kappa Opioid Receptor Antibody (aa321-370) LS-C120813

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (aa321-370) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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OPRK1 / Kappa Opioid Receptor Antibody LS-C749050

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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OPRK1 / Kappa Opioid Receptor Antibody (C-Terminus) LS-C37883

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, WB

Format:

Unconjugated

Price:

50 µl/$717

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OPRK1 / Kappa Opioid Receptor Antibody (Ab-369) LS-C821800

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (Ab-369) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$357

Select

OPRK1 / Kappa Opioid Receptor Antibody (phospho-Ser369) LS-C821799

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Mouse Polyclonal (pSer369) Antibody

Reactivity:

Mouse, Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

OPRK1 / Kappa Opioid Receptor Antibody (C-Terminus) LS-C37884

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

5 ml/$538

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OPRK1 / Kappa Opioid Receptor Antibody (290-370 aa, C-terminal) LS-C384281

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (290-370 aa, C-terminal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

OPRK1 / Kappa Opioid Receptor Antibody (aa181-209) LS-C323532

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (aa181-209) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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OPRK1 / Kappa Opioid Receptor Antibody (aa181-209, Biotin) LS-C265001

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (aa181-209) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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OPRK1 / Kappa Opioid Receptor Antibody (aa181-209, FITC) LS-C265002

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (aa181-209) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

OPRK1 / Kappa Opioid Receptor Antibody (aa181-209, APC) LS-C265000

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (aa181-209) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

OPRK1 / Kappa Opioid Receptor Antibody (aa181-209, Azide-free, HRP) LS-C265003

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (aa181-209) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

OPRK1 / Kappa Opioid Receptor Antibody (aa181-209, PE) LS-C265004

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (aa181-209) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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OPRK1 / Kappa Opioid Receptor Antibody (aa312-361) LS-C200300

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Human Polyclonal (aa312-361) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

OPRK1 / Kappa Opioid Receptor Antibody LS-C768732

Antibody:

OPRK1 / Kappa Opioid Receptor Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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