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Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation By similarity. May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.
Gene Name: | olfactomedin-like 3 |
Family/Subfamily: | Olfactomedin , not assigned-Olfactomedin |
Synonyms: | OLFML3, HOLF44, OLF44, Olfactomedin-like protein 3, HNOEL-iso, Olfactomedin-like 3 |
Target Sequences: | NM_020190 NP_064575.1 Q9NRN5 |
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