NUP98

nucleoporin 98kDa

Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML) and T-cell acute lymphocytic leukemia (T-ALL). This gene is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.

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Antibodies (50)

Type

Primary (50)

Target

NUP98 (50)

Reactivity

Human (42)

Mouse (26)

Rat (10)

Bat (3)

Bovine (6)

Chimpanzee (6)

Dog (5)

Gibbon (3)

Horse (6)

Monkey (6)

Rabbit (6)

Zebrafish (3)

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Application

IHC (4)

IHC-P (4)

WB (39)

ELISA (10)

IF (2)

IP (7)

Peptide-ELISA (1)

Host

rabbit (39)

mouse (11)

Product Group

IHCPlus (1)

Isotype

IgG (17)

IgG1 (1)

IgG2a,k (7)

Clonality

monoclonal mc (13)

polyclonal pc (37)

Clone

4G2 (1)

Format

APC (2)

APC Conjugated (3)

Biotin Conjugated (6)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (3)

Unconjugated (22)

Epitope

aa568-776 (8)

aa629-894 (8)

aa201-250 (4)

aa36-85 (4)

Leu518 (1)

Pro671 (1)

aa1-110 (1)

aa1650-1700 (1)

aa549-880 (1)

aa600-650 (1)

aa900-950 (1)

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Publications

No (50)

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NUP98 Antibody (aa201-250) LS-B10323

Antibody:

NUP98 Rabbit anti-Human Polyclonal (aa201-250) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$375

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NUP98 Antibody (aa201-250, HRP) LS-C457864

Antibody:

NUP98 Rabbit anti-Human Polyclonal (aa201-250) (HRP) Antibody

Reactivity:

Rabbit, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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NUP98 Antibody (aa201-250, Biotin) LS-C457862

Antibody:

NUP98 Rabbit anti-Human Polyclonal (aa201-250) (Biotin) Antibody

Reactivity:

Rabbit, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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NUP98 Antibody (aa201-250, FITC) LS-C457863

Antibody:

NUP98 Rabbit anti-Human Polyclonal (aa201-250) (FITC) Antibody

Reactivity:

Rabbit, Bovine, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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NUP98 Antibody (Pro671) LS-C73724

Antibody:

NUP98 Rabbit anti-Human Monoclonal (Pro671) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IP, WB

Format:

Unconjugated

Price:

20 µl/$468; 100 µl/$702

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NUP98 Antibody (Leu518) LS-C73725

Antibody:

NUP98 Rabbit anti-Human Monoclonal (Leu518) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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NUP98 Antibody LS-C330990

Antibody:

NUP98 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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NUP98 Antibody LS-C674962

Antibody:

NUP98 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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NUP98 Antibody LS-C752438

Antibody:

NUP98 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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NUP98 Antibody LS-C813062

Antibody:

NUP98 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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NUP98 Antibody LS-C768691

Antibody:

NUP98 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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NUP98 Antibody LS-C393563

Antibody:

NUP98 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$391

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NUP98 Antibody (aa600-650) LS-C288567

Antibody:

NUP98 Rabbit anti-Human Polyclonal (aa600-650) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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NUP98 Antibody (aa900-950) LS-C288566

Antibody:

NUP98 Rabbit anti-Human Polyclonal (aa900-950) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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NUP98 Antibody LS-C809791

Antibody:

NUP98 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

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NUP98 Antibody (clone 4G2) LS-C197811

Antibody:

NUP98 Mouse anti-Human Monoclonal (4G2) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$335

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NUP98 Antibody (aa1-110) LS-C131100

Antibody:

NUP98 Mouse anti-Human Monoclonal (aa1-110) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$705

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NUP98 Antibody (APC) LS-C518441

Antibody:

NUP98 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• APC

• Unconjugated
• APC

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NUP98 Antibody LS-C813060

Antibody:

NUP98 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Dog, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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NUP98 Antibody LS-C178364

Antibody:

NUP98 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Dog, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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NUP98 Antibody (aa568-776) LS-C295704

Antibody:

NUP98 Rabbit anti-Mouse Polyclonal (aa568-776) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206

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NUP98 Antibody (aa568-776, APC) LS-C716570

Antibody:

NUP98 Rabbit anti-Mouse Polyclonal (aa568-776) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$402; 200 µl/$484; 500 µl/$834; 1 ml/$991; 2 ml/$1,277; 5 ml/$2,395

• Unconjugated
• APC

• Unconjugated
• APC

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NUP98 Antibody (aa549-880) LS-C357488

Antibody:

NUP98 Rabbit anti-Human Polyclonal (aa549-880) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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NUP98 Antibody LS-C667762

Antibody:

NUP98 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386

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NUP98 Antibody (aa36-85) LS-C110364

Antibody:

NUP98 Rabbit anti-Human Polyclonal (aa36-85) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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