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NUMA1 / NUMA
nuclear mitotic apparatus protein 1
Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.
| Gene Name: | nuclear mitotic apparatus protein 1 |
| Synonyms: | NUMA1, Structural nuclear protein, NuMA protein, SP-H antigen, NUMA |
| Target Sequences: | NM_006185 NP_006176.2 Q14980 |
Publications (3)
1
Spectrum of Posttransplant Lymphoproliferations in NSG Mice and Their Association With EBV Infection After Engraftment of Pediatric Solid Tumors. Heather Tillman, Peter Vogel, Tiffani Rogers, Walter Akers, Jerold E Rehg. Veterinary pathology. 2020 May;57:445-456. [Full Text Article]
[PubMed:32202225]
[PMC:PMC7478125]
Related Antibodies: LS-B11047.
2
Morphologic and Immunohistochemical Characterization of Spontaneous Lymphoma/Leukemia in NSG Mice. Heather Tillman, Laura J Janke, Amy Funk, Peter Vogel, Jerold E Rehg. Veterinary pathology. 2020 January;57:160-171. [Full Text Article]
[PubMed:31736441]
[PMC:PMC8686194]
Related Antibodies: LS-B11047.
3
Development of Mast Cell and Eosinophil Hyperplasia and HLH/MAS-Like Disease in NSG-SGM3 Mice Receiving Human CD34+ Hematopoietic Stem Cells or Patient-Derived Leukemia Xenografts. Laura J Janke, Denise M Imai, Heather Tillman, Rosalinda Doty, Mark J Hoenerhoff, Jiajie J Xu, Zachary T Freeman, Portia Allen, Natalie Wall Fowlkes, Ilaria Iacobucci, Kirsten Dickerson, Charles G Mullighan, Peter Vogel, Jerold E Rehg. Veterinary pathology. 2021 January;58:181-204. [Full Text Article]
[PubMed:33208054]
[PMC:PMC8414369]
Related Antibodies: LS-B11047.
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NUMA1 / NUMA Rabbit anti-Human Polyclonal (aa900-950) Antibody
Human
IF, IHC, IHC-P
Unconjugated
50 µl/$460
NUMA1 / NUMA Rabbit anti-Human Polyclonal (aa1-339) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$485
NUMA1 / NUMA Mouse anti-Human Monoclonal (1C5) Antibody
Human
ELISA, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$460
293T Cells
Myc-DDK (Flag)
130.49 kDa
20 µg/$215
E. coli
6His, N-terminus
48.7 kDa
10 µg/$282; 50 µg/$450; 100 µg/$717; 200 µg/$897; 1 mg/$2,010; 500 µg/$1,547; 5 mg/$3,137; 2 mg/$2,198
NUMA1 / NUMA Rabbit anti-Human Polyclonal (310-390 aa, N-terminal) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
NUMA1 / NUMA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
NUMA1 / NUMA Rabbit anti-Human Polyclonal (aa315-364) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
NUMA1 / NUMA Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
NUMA1 / NUMA Mouse anti-Human Monoclonal (A73-B/D12) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
NUMA1 / NUMA Mouse anti-Human Monoclonal (Azide-free, BSA-free) (A73-B/D12) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
NUMA1 / NUMA Mouse anti-Human Monoclonal (SPM300) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
20 µg/$371; 100 µg/$574
NUMA1 / NUMA Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPM300) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
NUMA1 / NUMA Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
NUMA1 / NUMA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
NUMA1 / NUMA Rabbit anti-Human Polyclonal (aa900-950) Antibody
Human
IF, IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
NUMA1 / NUMA Mouse anti-Human Monoclonal (C02142) Antibody
Human
ICC, IP, WB
Unconjugated
100 µg/$403
NUMA1 / NUMA Rabbit anti-Human Polyclonal (aa2065-2115) Antibody
Human
IHC, IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
NUMA1 / NUMA Mouse anti-Human Monoclonal (B497) Antibody
Human
IHC, IHC-P
Unconjugated
0.5 ml/$328
NUMA1 / NUMA Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
NUMA1 / NUMA Rabbit anti-Human Polyclonal (aa1586-1635) Antibody
Human
WB
Unconjugated
100 µl/$424
NUMA1 / NUMA Rabbit anti-Human Polyclonal (aa1586-1635) (Biotin) Antibody
Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
NUMA1 / NUMA Rabbit anti-Human Polyclonal (aa1586-1635) (FITC) Antibody
Mouse, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
NUMA1 / NUMA Rabbit anti-Human Polyclonal (aa1700-2115) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
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