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NTF4 / Neurotrophin 4 is a member of a family of neurotrophic factors, neurotrophins, that control survival and differentiation of mammalian neurons. The expression of this gene is ubiquitous and less influenced by environmental signals. While knock-outs of other neurotrophins including nerve growth factor, brain-derived neurotrophic factor, and neurotrophin 3 prove lethal during early postnatal development, NTF5-deficient mice only show minor cellular deficits and develop normally to adulthood.
Gene Name: | neurotrophin 4 |
Family/Subfamily: | NGF Beta , not assigned-NGF Beta |
Synonyms: | NTF4, GLC1O, GLC10, Neurotrophic factor 5, NT-4, Neurotrophic factor 4, Neurotrophin-4, Neurotrophin-4 precursor, NT-5, NT4, NT5, NTF5, Neurotrophin 4, Neurotrophin-5, Neutrophic factor 4, NT-4/5 |
Target Sequences: | NM_006179 NP_006170.1 P34130 |
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