NRG3

neuregulin 3

NRG3 is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to activate the tyrosine phosphorylation of its cognate receptor, ERBB4, and is thought to influence neuroblast proliferation, migration and differentiation by signalling through ERBB4. NRG3 also promotes mammary differentiation during embryogenesis. Linkage studies have implicated this gene as a susceptibility locus for schizophrenia and schizoaffective disorder. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but their biological validity has not been verified.

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Antibodies (18)

ELISA Kits (9)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (18)

Recombinant (1)

Sandwich (8)

Sandwich CLIA (1)

Target

NRG3 (30)

Reactivity

Human (22)

Mouse (7)

Rat (3)

Bat (1)

Chicken (1)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Guinea pig (1)

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Application

IHC (12)

IHC-P (5)

WB (9)

ELISA (11)

Peptide-ELISA (2)

Host

rabbit (16)

mouse (1)

goat (1)

Product Group

IHCPlus (1)

Isotype

IgG (14)

IgG1 (1)

Clonality

monoclonal mc (1)

polyclonal pc (17)

Clone

06 (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (7)

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

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Epitope

Internal (7)

aa540-589 (4)

311-360 aa, Internal (1)

aa709-720 (1)

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No (30)

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Cell Culture Supernatants (1)

Cell Lysates (1)

Plasma (4)

Serum (4)

Tissue Homogenates (2)

Tag

6His-SUMO, N-terminus (1)

Myc-DDK (Flag) (2)

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Human (2)

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293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

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Purified (1)

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NRG3 Antibody (aa540-589) LS-B5783

Antibody:

NRG3 Rabbit anti-Human Polyclonal (aa540-589) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$485

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NRG3 Antibody (aa540-589, HRP) LS-C446766

Antibody:

NRG3 Rabbit anti-Human Polyclonal (aa540-589) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Rat, Chimpanzee, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

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NRG3 Antibody (aa540-589, Biotin) LS-C446765

Antibody:

NRG3 Rabbit anti-Human Polyclonal (aa540-589) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Rat, Chimpanzee, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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NRG3 Antibody (aa540-589, FITC) LS-C446764

Antibody:

NRG3 Rabbit anti-Human Polyclonal (aa540-589) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Rat, Chimpanzee, Gibbon, Human

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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NRG3 Antibody (311-360 aa, Internal) LS-C387731

Antibody:

NRG3 Rabbit anti-Human Polyclonal (311-360 aa, Internal) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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Human NRG3 (Sandwich ELISA) ELISA Kit - LS-F21014

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Human NRG3 Protein (Recombinant 6His-SUMO, N-terminus) (aa1-360) - LS-G56432

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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NRG3 Antibody (Internal) LS-C413291

Antibody:

NRG3 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$321

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NRG3 Antibody (Internal) LS-C323454

Antibody:

NRG3 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

200 µl/$734

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NRG3 Antibody (Internal, Biotin) LS-C246662

Antibody:

NRG3 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Biotin Conjugated

Price:

200 µl/$952

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NRG3 Antibody (Internal, FITC) LS-C246661

Antibody:

NRG3 Rabbit anti-Human Polyclonal (Internal) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

FITC Conjugated

Price:

200 µl/$952

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NRG3 Antibody (Internal, Azide-free, HRP) LS-C248951

Antibody:

NRG3 Rabbit anti-Human Polyclonal (Internal) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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NRG3 Antibody (Internal, APC) LS-C246659

Antibody:

NRG3 Rabbit anti-Human Polyclonal (Internal) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

APC Conjugated

Price:

200 µl/$952

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NRG3 Antibody (Internal, PE) LS-C246663

Antibody:

NRG3 Rabbit anti-Human Polyclonal (Internal) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• APC
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • APC
  • PE

Select

NRG3 Antibody LS-C743260

Antibody:

NRG3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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NRG3 Antibody LS-C807029

Antibody:

NRG3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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NRG3 Antibody (aa709-720) LS-C61770

Antibody:

NRG3 Goat anti-Human Polyclonal (aa709-720) Antibody

Reactivity:

Rabbit, Dog, Bat, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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NRG3 Antibody (clone 06, Preservative Free) LS-C820120

Antibody:

NRG3 Mouse anti-Human Monoclonal (Preservative Free) (06) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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NRG3 Antibody LS-C488520

Antibody:

NRG3 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µl/$412

Select

NRG3 Antibody (Preservative Free) LS-C818194

Antibody:

NRG3 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

Select

Human NRG3 (Sandwich ELISA) ELISA Kit - LS-F7145

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$730

Select

Human NRG3 (Sandwich ELISA) ELISA Kit - LS-F36780

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human NRG3 (CLIA) ELISA Kit - LS-F29626

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Chicken NRG3 (Sandwich ELISA) ELISA Kit - LS-F46053

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Guinea pig NRG3 (Sandwich ELISA) ELISA Kit - LS-F46054

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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