NRG1 / Heregulin / Neuregulin

neuregulin 1

Neuregulin 1 (NRG1) was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specifically expressed and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through interaction with ERBB receptors, NRG1 isoforms induce the growth and differentialtion of epithelial, neuronal, glial, and other types of cells.

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Products

ELISA Kits (32)

Type

Competitive EIA (1)

Custom (2)

Development Kit (2)

Sandwich (24)

Sandwich CLIA (3)

Target

NRG1 / Heregulin / Neuregulin (32)

Reactivity

Human (13)

Mouse (5)

Rat (7)

Chicken (2)

Guinea pig (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Product Group

DevKit Core (1)

DevKit DuoPlus (1)

Format

1000 Wells (1)

12 x 8-Well Microstrips (2)

96-Well Microplate (6)

96-Well Strip Plate (22)

Antibody Pair and Standard (1)

Publications

No (32)

Sample Type

Cell Culture Supernatants (8)

Cell Lysates (5)

Cell Supernatant (1)

Plasma (19)

Serum (19)

Tissue Homogenates (8)

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Mouse NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F5751

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F10529

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$632

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F5036

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$798

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F12193

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F31464

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

62.5 - 4000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$590

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DevKit Core Human NRG1 / Heregulin / Neuregulin ELISA Development Kit - LS-F31264

Type:

Development Kit

Format:

1000 Wells

Reactivity:

Human

Range:

32 - 2000 pg/ml

Detection:

Colorimetric - 405nm (ABTS)

Price:

1 Test/$540

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F50001

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

12.29 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$635

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Mouse NRG1 / Heregulin / Neuregulin (Competitive EIA) ELISA Kit - LS-F28504

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

250 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

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Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F3376

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

27.43 - 6667 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

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Rat NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F5750

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Tissue Homogenates

Price:

1 Plate/$750

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Rat NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F13361

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Rat NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F36673

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F36674

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F36675

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

78.125 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F39149

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$717

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Mouse NRG1 / Heregulin / Neuregulin (CLIA) ELISA Kit - LS-F30484

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human NRG1 / Heregulin / Neuregulin (CLIA) ELISA Kit - LS-F30144

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Chicken NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46042

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46044

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Guinea pig NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46045

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

1.25 - 80 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Rabbit NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46046

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

6.25 - 400 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Porcine NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46047

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Sheep NRG1 / Heregulin / Neuregulin (Sandwich ELISA) ELISA Kit - LS-F46048

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

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Rat NRG1 / Heregulin / Neuregulin (CLIA) ELISA Kit - LS-F37703

Type:

Sandwich CLIA

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

125 - 8000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human NRG1 / Heregulin / Neuregulin (Custom ELISA) ELISA Kit - LS-F50514

Type:

Custom

Format:

96-Well Microplate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$610

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