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NOVA1
neuro-oncological ventral antigen 1
NOVA1 is a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
| Gene Name: | neuro-oncological ventral antigen 1 |
| Synonyms: | NOVA1, Nova-1, Onconeural ventral antigen 1, RNA-binding protein Nova-1, Paraneoplastic Ri antigen |
| Target Sequences: | NM_002515 NP_002506.2 P51513 |
Publications (3)
1
Dynamic expression pattern of neuro-oncological ventral antigen 1 (Nova1) in the rat brain after focal cerebral ischemia/reperfusion insults. Li H, Sun C, Wang Y, Gao Y, Liu Y, Gao Y, Li X, Zhang C. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 2013 61:45-54. (WB, IHC-P; Rat)
[Full Text Article]
[PubMed:23042482]
[PMC:PMC3534313]
2
High expression of neuro-oncological ventral antigen 1 correlates with poor prognosis in hepatocellular carcinoma. Zhang YA, Zhu JM, Yin J, Tang WQ, Guo YM, Shen XZ, Liu TT. PloS one. 2014 9:e90955. (WB; Human)
[Full Text Article]
[PubMed:24608171]
[PMC:PMC3946567]
Related Antibodies: LS-B3259.
3
RNA binding protein Nova1 promotes tumor growth in vivo and its potential mechanism as an oncogene may due to its interaction with GABAA Receptor-?2. Zhang YA, Liu HN, Zhu JM, Zhang DY, Shen XZ, Liu TT. Journal of biomedical science. 2016 23:71. (WB; Human)
[Full Text Article]
[PubMed:27733149]
[PMC:PMC5062898]
Related Antibodies: LS-B3259.
☰ Filters
Products
Proteins
(12)
Type
Over-Expression Lysate
(4)
Recombinant
(8)
Target
NOVA1
(12)
Publications
No
(12)
Tag
6His, N-terminus
(1)
GST
(2)
GST, N-terminus
(1)
His, N-Terminal
(1)
His-T7, N-terminus
(1)
Myc-DDK (Flag)
(6)
Species
Human
(10)
Source
293T Cells
(2)
E. coli
(2)
HEK 293 Cells
(5)
Wheat Germ Extract
(3)
Purification
Purified
(4)
E. coli
His-T7, N-terminus
24.8kDa
10 µg/$272; 50 µg/$387; 200 µg/$772; 100 µg/$620; 1 mg/$1,834; 500 µg/$1,393; 5 mg/$2,794; 2 mg/$2,016
HEK 293 Cells
His, N-Terminal
52 kDa (55-75 kDa reducing conditions)
10 µg/$289; 200 µg/$646; 50 µg/$360
Wheat Germ Extract
GST
81.29 kDa
10 µg/$479; 25 µg/$670
Wheat Germ Extract
GST
78.1 kDa
2 µg/$439
HEK 293 Cells
Myc-DDK (Flag)
51.5 kDa
20 µg/$1,107
HEK 293 Cells
Myc-DDK (Flag)
49.1 kDa
20 µg/$1,107
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
E. coli
6His, N-terminus
56 kDa
10 µg/$265; 100 µg/$365; 50 µg/$315
HEK 293 Cells
Myc-DDK (Flag)
51.5 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
49.1 kDa
100 µg/$710
293T Cells
Myc-DDK (Flag)
51.5 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
49.1 kDa
20 µg/$215
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