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NOVA1 is a neuron-specific RNA-binding protein, a member of the Nova family of paraneoplastic disease antigens, that is recognized and inhibited by paraneoplastic antibodies. These antibodies are found in the sera of patients with paraneoplastic opsoclonus-ataxia, breast cancer, and small cell lung cancer. Alternatively spliced transcripts encoding distinct isoforms have been described.
Gene Name: | neuro-oncological ventral antigen 1 |
Synonyms: | NOVA1, Nova-1, Onconeural ventral antigen 1, RNA-binding protein Nova-1, Paraneoplastic Ri antigen |
Target Sequences: | NM_002515 NP_002506.2 P51513 |
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