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NOTCH3
notch 3
NOTCH3 is the third discovered human homologue of the Drosophilia melanogaster type I membrane protein notch. In Drosophilia, notch interaction with its cell-bound ligands (delta, serrate) establishes an intercellular signalling pathway that plays a key role in neural development. Homologues of the notch-ligands have also been identified in human, but precise interactions between these ligands and the human notch homologues remains to be determined. Mutations in NOTCH3 have been identified as the underlying cause of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).
| Gene Name: | notch 3 |
| Family/Subfamily: | Fibronectin , not assigned-Fibronectin |
| Synonyms: | NOTCH3, CASIL, CADASIL, Notch 3, Notch (Drosophila) homolog 3, Notch homolog 3, Notch homolog 3 (Drosophila) |
| Target Sequences: | NM_000435 NP_000426.2 Q9UM47 |
Publications (2)
1
Notch4 overexpression in ameloblastoma correlates with the solid/multicystic phenotype. Siar CH, Nagatsuka H, Chuah KS, Rivera RS, Nakano K, Ng KH, Kawakami T. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics. 2010 110:224-33. (IHC-P; Human)
[PubMed:20659700]
2
Notch signaling and ghost cell fate in the calcifying cystic odontogenic tumor. Siar CH, Kawakami T, Buery RR, Nakano K, Tomida M, Tsujigiwa H, Han PP, Nagatsuka H, Ng KH. European journal of medical research. 2011 16:501-6. (IHC-P; Human)
[PubMed:22027644]
[PMC:PMC3351808]
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(42)
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NOTCH3
(42)
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(41)
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Publications
No
(42)
NOTCH3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
NOTCH3 Goat anti-Human Polyclonal (aa2306-2318) Antibody
Mouse, Rat, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µg/$485
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
NOTCH3 Sheep anti-Human Polyclonal (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$839
NOTCH3 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
30 µl/$255; 50 µl/$271; 100 µl/$299; 200 µl/$351
NOTCH3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
60 µl/$460
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) Antibody
Human
ELISA, IHC
Unconjugated
200 µl/$734
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (Biotin) Antibody
Human
ELISA, IHC
Biotin Conjugated
200 µl/$952
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (FITC) Antibody
Human
ELISA, IHC
FITC Conjugated
200 µl/$952
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (Azide-free) (HRP) Antibody
Human
ELISA, IHC
HRP Conjugated, Azide-free
200 µl/$952
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (APC) Antibody
Human
ELISA, IHC
APC Conjugated
200 µl/$952
NOTCH3 Rabbit anti-Human Polyclonal (aa2291-2321) (PE) Antibody
Human
ELISA, IHC
PE Conjugated
200 µl/$952
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) (487CT6.9.2) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) (Biotin) (487CT6.9.2) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) (FITC) (487CT6.9.2) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) (PE) (487CT6.9.2) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) (Azide-free) (HRP) (487CT6.9.2) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
NOTCH3 Mouse anti-Human Monoclonal (aa47-156) (2E4D11) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
NOTCH3 Mouse anti-Human Monoclonal (aa47-156) (3E2D9) Antibody
Human
ELISA, WB
Unconjugated
100 µl/$459
NOTCH3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
50 µg/$294; 100 µg/$360
NOTCH3 Mouse anti-Human Monoclonal (aa47-156) (1G5) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
NOTCH3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Rat, Human
IHC, IHC-Fr
Unconjugated
100 µl/$551
NOTCH3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
NOTCH3 Mouse anti-Human Monoclonal (aa2291-2321) Antibody
Human
WB
Unconjugated
400 µl/$393
NOTCH3 Rabbit anti-Human Polyclonal (aa2053-2318) Antibody
Human
WB
Unconjugated
100 µl/$318; 200 µl/$364; 500 µl/$518; 1 ml/$595; 2 ml/$822; 5 ml/$1,345
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