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NOS2 / iNOS
nitric oxide synthase 2, inducible
Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.
| Gene Name: | nitric oxide synthase 2, inducible |
| Synonyms: | NOS2, Hepatocyte NOS, HEP-NOS, Inducible NOS, NOS, type II, NOS type II, Inducible NO synthase, NOS2A, INOS, NOS |
| Target Sequences: | NM_000625 NP_000616.3 P35228 |
Publications (8)
1
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Yang A, Herter-Sprie G, Zhang H, Lin EY, Biancur D, Wang X, Deng J, Hai J, Yang S, Wong KK, Kimmelman AC. Cancer discovery. 2018 March;8:276-287. [Full Text Article]
[PubMed:29317452]
[PMC:PMC5835190]
2
Acquisition of heroin conditioned immunosuppression requires IL-1 signaling in the dorsal hippocampus. Lebonville CL, Jones ME, Hutson LW, Cooper LB, Fuchs RA, Lysle DT. Brain, behavior, and immunity. 2016 August;56:325-34. [Full Text Article]
[PubMed:27072068]
[PMC:PMC4917416]
3
Interleukin-1 signaling in the basolateral amygdala is necessary for heroin-conditioned immunosuppression. Hutson LW, Lebonville CL, Jones ME, Fuchs RA, Lysle DT. Brain, behavior, and immunity. 2017 May;62:171-179. [Full Text Article]
[PubMed:28131792]
[PMC:PMC5828772]
☰ Filters
Products
Proteins
(12)
Type
Over-Expression Lysate
(2)
Recombinant
(10)
Target
NOS2 / iNOS
(12)
Publications
No
(12)
Tag
GST, N-terminus
(1)
His
(5)
His, N-Terminal
(2)
His-T7
(1)
Myc-DDK (Flag)
(3)
Species
Human
(6)
Mouse
(3)
Rat
(2)
Source
293T Cells
(1)
E. coli
(8)
HEK 293 Cells
(2)
Wheat Germ Extract
(1)
Low Endotoxin Level
Low endotoxin level
(1)
E. coli
His, N-Terminal
22.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
E. coli
His, N-Terminal
21.1 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
293T Cells
Myc-DDK (Flag)
130.9 kDa
20 µg/$215
E. coli
His
20 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His
6.3 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
E. coli
His-T7
30.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
HEK 293 Cells
Myc-DDK (Flag)
130.9 kDa
20 µg/$1,107
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
E. coli
His
19.6 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
E. coli
His
16.2 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
HEK 293 Cells
Myc-DDK (Flag)
130.9 kDa
100 µg/$710
E. coli
109 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
12.1 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
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