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Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
Gene Name: | NME/NM23 nucleoside diphosphate kinase 3 |
Synonyms: | NME3, DR-nm23, NDP kinase 3, NDK 3, NDPKC, NM23-H3, NM23H3, NDP kinase C, NDPK-C, C371H6.2 |
Target Sequences: | NM_002513 NP_002504.2 Q13232 |
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